INT286030

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Context Info
Confidence 0.07
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.34
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Creb1, Bcl2) nucleus (Creb1, Bcl2) transcription factor binding (Creb1, Bcl2)
nucleoplasm (Creb1) aging (Bcl2) DNA binding (Creb1)
Creb1 (Rattus norvegicus)
Bcl2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Spinal cord 8 5.00 Very Low Very Low Very Low
Sciatic nerve 8 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Neuropathic pain 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Eae 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 7 98.92 Very High Very High Very High
Injury 16 68.56 Quite High
Ganglion Cysts 1 50.00 Quite Low
Neuroblastoma 9 31.16 Quite Low
Apoptosis 29 30.48 Quite Low
Cancer 7 20.48 Low Low
Repression 1 10.32 Low Low
Death 19 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 4 5.00 Very Low Very Low Very Low
Targeted Disruption 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CREB undergoes phosphorylation and exerts a
               prosurvival effect by regulating the transcription of prosurvival factors, including
                   bcl-2, in response to oxidative stress [18], [26], [39], [49], [50].
CREB Regulation (regulating) of Transcription (transcription) of bcl-2 associated with stress
1) Confidence 0.07 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2771921 Disease Relevance 0.34 Pain Relevance 0

General Comments

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