INT286092

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Context Info
Confidence 0.06
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 2.48
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeleton (Afap1) cytoplasm (Afap1)
Anatomy Link Frequency
germline 1
Afap1 (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 3 6.72 Low Low
imagery 5 5.00 Very Low Very Low Very Low
Bile 4 5.00 Very Low Very Low Very Low
abdominal pain 3 5.00 Very Low Very Low Very Low
COX-2 inhibitor 2 5.00 Very Low Very Low Very Low
methotrexate 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
Dismenorea 1 5.00 Very Low Very Low Very Low
vincristine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Familial Adenomatous Polyposis 240 100.00 Very High Very High Very High
Cancer 66 87.36 High High
Polyps 68 86.92 High High
Liver Cancer 4 76.12 Quite High
Adenocarcinoma 9 75.04 Quite High
Adenoma 58 72.64 Quite High
Adhesions 3 57.84 Quite High
Adenomatous Polyps 12 42.52 Quite Low
Thyroid Neoplasm 3 33.28 Quite Low
Glioblastoma 2 24.36 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Classic FAP is inherited as an autosomal dominant trait and results from a germline APC mutation; AFAP is mostly caused by specific APC mutations.
Positive_regulation (caused) of AFAP in germline associated with familial adenomatous polyposis
1) Confidence 0.06 Published 2009 Journal Orphanet J Rare Dis Section Body Doc Link PMC2772987 Disease Relevance 2.48 Pain Relevance 0

General Comments

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