INT286097

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Context Info
Confidence 0.05
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.72
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeleton (Afap1) cytoplasm (Afap1)
Anatomy Link Frequency
proximal 2
Afap1 (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 10 5.00 Very Low Very Low Very Low
Bile 8 5.00 Very Low Very Low Very Low
Central nervous system 6 5.00 Very Low Very Low Very Low
abdominal pain 6 5.00 Very Low Very Low Very Low
COX-2 inhibitor 4 5.00 Very Low Very Low Very Low
methotrexate 2 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
adenocard 2 5.00 Very Low Very Low Very Low
Dismenorea 2 5.00 Very Low Very Low Very Low
vincristine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Familial Adenomatous Polyposis 480 100.00 Very High Very High Very High
Disease 50 91.44 High High
Anxiety Disorder 8 80.16 Quite High
Adenoma 116 73.60 Quite High
Cancer 132 69.40 Quite High
Desmoid Disease 48 57.92 Quite High
Colon Cancer 66 53.00 Quite High
Hemorrhage 6 5.04 Very Low Very Low Very Low
Polyps 136 5.00 Very Low Very Low Very Low
Adenomatous Polyps 24 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The genetic alteration in AFAP is associated with APC mutations occurring most commonly at the 5' or at the 3' end of the gene proximal to codon 1517 or distal to codon 1900 [39].
AFAP Binding (associated) of in proximal associated with familial adenomatous polyposis
1) Confidence 0.05 Published 2009 Journal Orphanet J Rare Dis Section Body Doc Link PMC2772987 Disease Relevance 0.71 Pain Relevance 0
Mutations contributing to classical FAP occur between exon 5 and the 5' portion of exon 15, whereas those associated with AFAP tend to cluster in the extreme 5' portion of the gene and the 3' portion of exon 15 proximal to codon 1517 or distal to codon 1900 [35,36].
AFAP Binding (associated) of in proximal associated with familial adenomatous polyposis
2) Confidence 0.05 Published 2009 Journal Orphanet J Rare Dis Section Body Doc Link PMC2772987 Disease Relevance 1.02 Pain Relevance 0

General Comments

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