INT286184

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Context Info
Confidence 0.39
First Reported 2009
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 7
Disease Relevance 2.16
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

helicase activity (Blm) DNA binding (Blm) cytoplasm (Blm)
chromosome organization (Blm) nucleolus (Blm) ATPase activity (Blm)
Anatomy Link Frequency
F98 1
brain 1
Blm (Rattus norvegicus)
Pain Link Frequency Relevance Heat
imagery 28 92.24 High High
cva 21 20.16 Low Low
ischemia 14 10.20 Low Low
Analgesic 7 5.00 Very Low Very Low Very Low
bradykinin 7 5.00 Very Low Very Low Very Low
isoflurane 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 7 97.68 Very High Very High Very High
Cancer 308 95.20 Very High Very High Very High
Toxicity 70 79.80 Quite High
Sprains And Strains 7 59.36 Quite High
Anaplastic Astrocytoma 7 54.20 Quite High
Glioblastoma 21 53.12 Quite High
Edema 63 51.28 Quite High
Glioma 56 50.44 Quite High
Colon Cancer 7 38.12 Quite Low
Death 14 32.16 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
If this ratio of total dose to brain concentration is similar for BLM, this suggests a drug concentration of approximately 7.5 ?
Gene_expression (similar) of BLM in brain
1) Confidence 0.39 Published 2009 Journal J Neurooncol Section Body Doc Link PMC2773371 Disease Relevance 0.27 Pain Relevance 0.04
Control groups consisted of; no treatment, ETXp, or BLM no light, and PDT only.
Neg (no) Gene_expression (light) of BLM
2) Confidence 0.39 Published 2009 Journal J Neurooncol Section Body Doc Link PMC2773371 Disease Relevance 0.26 Pain Relevance 0
1, which produced a 65% inhibition of F98 cell proliferation, only a slight decrease in cell migration was observed.Fig. 3Effects of BLM on F98 cell migration from multicell spheroids.
Gene_expression (3Effects) of BLM in F98
3) Confidence 0.39 Published 2009 Journal J Neurooncol Section Body Doc Link PMC2773371 Disease Relevance 0.44 Pain Relevance 0
1) of BLM-containing medium (Sigma, St.
Gene_expression (containing) of BLM
4) Confidence 0.39 Published 2009 Journal J Neurooncol Section Body Doc Link PMC2773371 Disease Relevance 0.17 Pain Relevance 0
The in vitro data shown in Fig. 1a suggest, that a BLM concentration in excess of 5 ?
Gene_expression (concentration) of BLM
5) Confidence 0.39 Published 2009 Journal J Neurooncol Section Body Doc Link PMC2773371 Disease Relevance 0.54 Pain Relevance 0.05
Even at a BLM concentration of 1 ?
Gene_expression (concentration) of BLM
6) Confidence 0.39 Published 2009 Journal J Neurooncol Section Body Doc Link PMC2773371 Disease Relevance 0.42 Pain Relevance 0
Increasing concentrations of BLM caused a decreasing survival of colony forming cells and at a concentration of 5 ?
Gene_expression (concentrations) of BLM
7) Confidence 0.39 Published 2009 Journal J Neurooncol Section Body Doc Link PMC2773371 Disease Relevance 0.05 Pain Relevance 0

General Comments

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