INT286196

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Context Info
Confidence 0.36
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.95
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Psmb9) nucleus (Psmb9) cytoplasm (Psmb9)
Psmb9 (Mus musculus)
Pain Link Frequency Relevance Heat
spinal inflammation 2 91.36 High High
psoriasis 2 87.52 High High
midbrain 26 86.00 High High
alcohol 2 78.96 Quite High
Inflammation 16 76.00 Quite High
Sicca syndrome 2 72.56 Quite High
Glutamate 10 5.00 Very Low Very Low Very Low
Ventral tegmentum 7 5.00 Very Low Very Low Very Low
monoamine 5 5.00 Very Low Very Low Very Low
cytokine 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Autoimmune Disease 14 99.84 Very High Very High Very High
Disease 96 92.40 High High
Low Back Pain 2 91.36 High High
Hashimoto Disease 30 90.60 High High
Stress 11 90.36 High High
Hypopigmentation 2 89.04 High High
Hypothyroidism 32 88.92 High High
Psoriasis 2 87.52 High High
INFLAMMATION 17 76.00 Quite High
Systemic Lupus Erythematosus 2 75.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
After blocking aspecific binding with 5% normal goat serum, sections were incubated with the primary antibody; rabbit anti proteasome subunit (LMP2, LMP7, LMP10, PA28?
LMP2 Binding (subunit) of
1) Confidence 0.36 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2773418 Disease Relevance 0 Pain Relevance 0.04
Some studies have positively linked LMP2 to autoimmunity.
LMP2 Binding (linked) of associated with autoimmune disease
2) Confidence 0.36 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2773418 Disease Relevance 1.42 Pain Relevance 0.21
Parkin interacts with the 26S proteosome through its ubiquitin ligase domain facilitating the recognition of ubiquitinated substrates by the proteasomal activator PA700 (Pickart, 2004).
proteosome Binding (interacts) of
3) Confidence 0.36 Published 2010 Journal Frontiers in Neuroanatomy Section Body Doc Link PMC2978035 Disease Relevance 0.53 Pain Relevance 0.08

General Comments

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