INT286197

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Context Info
Confidence 0.49
First Reported 2009
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 2.44
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Psmb9) nucleus (Psmb9) cytoplasm (Psmb9)
Anatomy Link Frequency
thyroid 2
thyroid glands 2
Psmb9 (Mus musculus)
Pain Link Frequency Relevance Heat
Sicca syndrome 3 80.32 Quite High
psoriasis 3 72.56 Quite High
spinal inflammation 3 71.16 Quite High
alcohol 3 70.20 Quite High
Inflammation 15 55.92 Quite High
cytokine 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 6 99.38 Very High Very High Very High
Hypothyroidism 48 99.32 Very High Very High Very High
Hyperthyroidism 18 98.60 Very High Very High Very High
Targeted Disruption 150 96.00 Very High Very High Very High
Autoimmune Disease 21 94.16 High High
Thyroiditis 9 86.48 High High
Carcinoma 24 84.44 Quite High
Syndrome 3 80.32 Quite High
Increased Venous Pressure Under Development 3 79.56 Quite High
Systemic Lupus Erythematosus 3 79.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For example, Vives-Pi and colleagues, studying eight patients with Graves disease patients and four with type 1 diabetes, reported that thyroid glands expressed high but variable levels of LMP2 and LMP7, whereas pancreases had levels similar to those found in healthy controls [21].
Positive_regulation (levels) of Gene_expression (expressed) of LMP2 in thyroid glands associated with diabetes mellitus and hyperthyroidism
1) Confidence 0.49 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2773418 Disease Relevance 1.16 Pain Relevance 0.15
Interestingly, the lack of LMP2 ameliorated the hypothyroidism seen in thyr-IFN?
Positive_regulation (lack) of Neg (lack) Gene_expression (lack) of LMP2 associated with hypothyroidism
2) Confidence 0.49 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2773418 Disease Relevance 1.29 Pain Relevance 0.03
Primary antibody was diluted for human thyroid sections as following; LMP2 (1?
Positive_regulation (following) of Gene_expression (diluted) of LMP2 in thyroid
3) Confidence 0.42 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2773418 Disease Relevance 0 Pain Relevance 0.04

General Comments

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