INT286229

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Context Info
Confidence 0.07
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.01
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Psmb9, Tpo) mitochondrion (Tpo) peptidase activity (Psmb9)
oxidoreductase activity (Tpo) plasma membrane (Tpo) nucleus (Psmb9)
Anatomy Link Frequency
thyroid 1
Psmb9 (Mus musculus)
Tpo (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 5 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Sicca syndrome 1 5.00 Very Low Very Low Very Low
psoriasis 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
spinal inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 50 88.24 High High
Hypothyroidism 16 82.72 Quite High
Hyperthyroidism 6 67.84 Quite High
Body Weight 1 53.36 Quite High
Hashimoto Disease 15 5.00 Very Low Very Low Very Low
Carcinoma 8 5.00 Very Low Very Low Very Low
Autoimmune Disease 7 5.00 Very Low Very Low Very Low
Thyroid Neoplasm 7 5.00 Very Low Very Low Very Low
Adenoma 6 5.00 Very Low Very Low Very Low
INFLAMMATION 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
During these studies we also noted that thyroid follicular cells from mice lacking only LMP2 were flatter than those observed in wild type controls (Figure S2A), suggesting an effect of LMP2 on thyroid hormonogenesis.
LMP2 Regulation (effect) of thyroid in thyroid
1) Confidence 0.07 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2773418 Disease Relevance 1.01 Pain Relevance 0

General Comments

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