INT286265

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Context Info
Confidence 0.20
First Reported 2009
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.06
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (GPSM2) nucleolus (GPSM2) nucleus (GPSM2)
cytoplasm (GPSM2)
Anatomy Link Frequency
neuronal 1
GPSM2 (Homo sapiens)
Pain Link Frequency Relevance Heat
anesthesia 8 83.80 Quite High
positron emission tomography 2 78.56 Quite High
imagery 3 64.72 Quite High
Central nervous system 47 63.52 Quite High
Buprenorphine 2 60.00 Quite High
analgesia 2 58.36 Quite High
isoflurane 2 49.20 Quite Low
ketamine 5 45.92 Quite Low
tetrodotoxin 11 5.00 Very Low Very Low Very Low
Deafferentation 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ocular Hypertension 142 98.68 Very High Very High Very High
Neurodegenerative Disease 6 85.52 High High
Glaucoma 18 83.24 Quite High
Optic Nerve Injuries 70 71.08 Quite High
Injury 13 66.12 Quite High
Frailty 8 57.04 Quite High
Ganglion Cysts 17 56.28 Quite High
Death 6 5.00 Very Low Very Low Very Low
INFLAMMATION 6 5.00 Very Low Very Low Very Low
Hypersensitivity 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Sasaoka et al. [69] reported GFAP immunoreactivity as well as neuronal cell loss in the LGN after 11–18 weeks of unilateral OHT in two cynomolgus monkeys.
Negative_regulation (loss) of LGN in neuronal associated with ocular hypertension
1) Confidence 0.20 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2773743 Disease Relevance 0.99 Pain Relevance 0.10
The LGN was blocked in the coronal plane, frozen on dry ice and stored at ?
Negative_regulation (blocked) of LGN
2) Confidence 0.20 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2773743 Disease Relevance 0.07 Pain Relevance 0.20
Although LGN development occurs in utero in primates [39,40], we expected to observe strong expression of MHCI-HC (MHCI heavy chain) in newborn animals, as the expression of these genes persists in the LGN of adult rodents and cats [12,15].
Negative_regulation (persists) of LGN
3) Confidence 0.02 Published 2011 Journal Behav Brain Funct Section Body Doc Link PMC3023691 Disease Relevance 0 Pain Relevance 0

General Comments

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