INT286294

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Context Info
Confidence 0.01
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.54
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Hspb8) intracellular (Hspb8) response to stress (Hspb8)
cytoplasm (Hspb8)
Anatomy Link Frequency
eosinophil 1
Hspb8 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 14 93.76 High High
Inflammatory response 6 89.72 High High
antagonist 10 62.40 Quite High
Inflammatory mediators 1 21.04 Low Low
cytokine 12 5.00 Very Low Very Low Very Low
anesthesia 9 5.00 Very Low Very Low Very Low
Arthritis 4 5.00 Very Low Very Low Very Low
Multiple sclerosis 2 5.00 Very Low Very Low Very Low
rheumatoid arthritis 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pulmonary Eosinophilia 2 99.92 Very High Very High Very High
Obesity 167 99.64 Very High Very High Very High
Asthma 38 96.04 Very High Very High Very High
Rheumatoid Arthritis 18 94.84 High High
INFLAMMATION 21 93.76 High High
Weight Loss 7 92.28 High High
Hypersensitivity 42 88.36 High High
Overweight 8 76.60 Quite High
Weight Gain 6 67.92 Quite High
Eosinophilia 4 52.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
VAD reduced serum IgE and IgG1 responses, pulmonary eosinophilia, and the levels of IL-4 and IL-5 in BALF specimen [39].
Regulation (responses) of IgE associated with pulmonary eosinophilia
1) Confidence 0.01 Published 2009 Journal Nutr Metab (Lond) Section Body Doc Link PMC2773769 Disease Relevance 0.28 Pain Relevance 0.04
Our results show that treatment with some extra-supplementation of ATRA produces an up-regulation of IgE in serum.
Regulation (regulation) of IgE
2) Confidence 0.01 Published 2009 Journal Nutr Metab (Lond) Section Body Doc Link PMC2773769 Disease Relevance 0.21 Pain Relevance 0.03
However, there are no changes in AHR or inhaled nitric oxide.51,52 BMI does not seem to affect eosinophil counts or serum IgE levels either.53
Regulation (affect) of IgE in eosinophil associated with obesity
3) Confidence 0.00 Published 2010 Journal Int J Gen Med Section Body Doc Link PMC2990395 Disease Relevance 2.05 Pain Relevance 0.09

General Comments

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