INT286337

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Context Info
Confidence 0.07
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.37
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (PSENEN, Psen1) endoplasmic reticulum (PSENEN, Psen1) peptidase activity (PSENEN, Psen1)
plasma membrane (PSENEN, Psen1) mitochondrion (Psen1) intracellular (Psen1)
PSENEN (Homo sapiens)
Psen1 (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 10 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 10 98.68 Very High Very High Very High
Alzheimer's Dementia 11 97.90 Very High Very High Very High
Infection 3 5.00 Very Low Very Low Very Low
Toxicity 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Aging 1 5.00 Very Low Very Low Very Low
Viral Infection 1 5.00 Very Low Very Low Very Low
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
42/40 ratio due to familial AD mutations correlates with a change in the PS1 NT-CT proximity we hypothesized that an elongation of the Pen2 NT may have an effect on PS1 conformation similar to that of FAD PS1 mutations.
Pen2 Regulation (effect) of PS1 associated with alzheimer's dementia and disease
1) Confidence 0.07 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2773935 Disease Relevance 0.37 Pain Relevance 0

General Comments

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