INT286352

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Context Info
Confidence 0.24
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.32
Pain Relevance 0.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL6, IL8) extracellular region (IL6, IL8) signal transduction (IL8)
aging (IL6) intracellular (IL8)
Anatomy Link Frequency
amnion 2
IL6 (Homo sapiens)
IL8 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 46 99.08 Very High Very High Very High
cytokine 62 98.56 Very High Very High Very High
Inflammatory response 7 33.16 Quite Low
Pain 1 14.16 Low Low
Opioid 2 8.56 Low Low
anesthesia 8 5.00 Very Low Very Low Very Low
Inflammatory stimuli 4 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 58 99.08 Very High Very High Very High
Stress 7 99.00 Very High Very High Very High
Urinary Tract Infection 26 92.64 High High
Infection 14 80.72 Quite High
Pre-term Labor 4 65.56 Quite High
Injury 2 57.92 Quite High
Candida Infection 1 54.24 Quite High
Adhesions 1 45.28 Quite Low
Adult Respiratory Distress Syndrome 1 42.56 Quite Low
Sepsis 1 41.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The IL-8 levels are expected to increase along with IL-6 because it also is an inflammatory cytokine.
IL-6 Positive_regulation (increase) of Gene_expression (levels) of IL-8 associated with inflammation and cytokine
1) Confidence 0.24 Published 2010 Journal Korean Journal of Anesthesiology Section Body Doc Link PMC2876852 Disease Relevance 0.62 Pain Relevance 0.12
Our results with IL-6 and IL-8, that exposure to LPS on the amnion side stimulated IL-6 and IL-8 release on the choriodecidual side, provide new examples of inflammatory cytokine signaling across the gestational membranes.
IL-6 Positive_regulation (results) of Gene_expression (exposure) of IL-8 in amnion associated with inflammation and cytokine
2) Confidence 0.11 Published 2009 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2774314 Disease Relevance 0.70 Pain Relevance 0.36

General Comments

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