INT286376

Context Info Confidence 0.43 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 3 Disease Relevance 0.17 Pain Relevance 0

cytosol (Akt2) transport (Akt2) mitochondrion (Akt2) plasma membrane (Akt2) nucleus (Akt2) carbohydrate metabolic process (Akt2)

Anatomy Link Frequency eyes 6 Akt2 (Mus musculus)

Pain Link Frequency Relevance Heat anesthesia 6 5.00 Nerve growth factor 3 5.00 GABAergic 3 5.00

Disease Link Frequency Relevance Heat Myopia 39 56.40 Death 6 5.00 Injury 6 5.00 Ganglion Cysts 6 5.00 Hyperopia 3 5.00 Overdose 3 5.00 Nonsyndromic Deafness 3 5.00 Adhesions 3 5.00 Refractive Errors 3 5.00 Retina Disease 3 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Other interesting candidates were Akt2, which was up-regulated after 30 min of deprivation and Mapk8ip3, a neuron specific JNK binding and scaffolding protein that was temporally regulated in the diffuser-treated eyes only.

Positive_regulation (after) of Positive_regulation (regulated) of Akt2 in eyes

1) Confidence 0.43 Published 2007 Journal Molecular Vision Section Abstract Doc Link PMC2774458 Disease Relevance 0.06 Pain Relevance 0

Other interesting candidates were Akt2, which was up-regulated after 30 min of deprivation and Mapk8ip3, a neuron specific JNK binding and scaffolding protein that was temporally regulated in the diffuser-treated eyes only.

Positive_regulation (up) of Positive_regulation (regulated) of Akt2 in eyes

2) Confidence 0.43 Published 2007 Journal Molecular Vision Section Abstract Doc Link PMC2774458 Disease Relevance 0.06 Pain Relevance 0

Other interesting candidates were Akt2, which was up-regulated after 30 min of deprivation and Mapk8ip3, a neuron specific JNK binding and scaffolding protein that was temporally regulated in the diffuser-treated eyes only.

Positive_regulation (-) of Positive_regulation (regulated) of Akt2 in eyes

3) Confidence 0.43 Published 2007 Journal Molecular Vision Section Abstract Doc Link PMC2774458 Disease Relevance 0.06 Pain Relevance 0

General Comments

This test has worked.