INT286394

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Context Info
Confidence 0.42
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.08
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Fos) DNA binding (Fos) transcription factor binding (Fos)
Anatomy Link Frequency
eyes 2
neurons 2
Fos (Mus musculus)
Pain Link Frequency Relevance Heat
GABAergic 6 89.12 High High
qutenza 5 79.48 Quite High
Dorsal horn 12 77.64 Quite High
Spinal cord 25 67.92 Quite High
Hippocampus 6 63.16 Quite High
Lasting pain 7 8.08 Low Low
Acute pain 2 5.36 Low Low
Pain 21 5.00 Very Low Very Low Very Low
bDMF 18 5.00 Very Low Very Low Very Low
long-term potentiation 12 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nociception 41 99.74 Very High Very High Very High
Aids-related Complex 131 99.06 Very High Very High Very High
Myopia 13 75.84 Quite High
Radiation Sickness 1 65.00 Quite High
Targeted Disruption 35 56.20 Quite High
Ganglion Cysts 3 49.04 Quite Low
Pain 28 8.08 Low Low
Depression 7 5.00 Very Low Very Low Very Low
Neuropathic Pain 7 5.00 Very Low Very Low Very Low
Nervous System Injury 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, the analysis by real-time RT-PCR also revealed a down-regulation of cFos mRNA in the diffuser-treated eyes after 30 min and even after 6+6 h.
Negative_regulation (down) of Negative_regulation (regulation) of cFos mRNA in eyes
1) Confidence 0.42 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2774458 Disease Relevance 0.14 Pain Relevance 0.04
Expression of Arc/Arg3.1 mRNA following nociceptive stimulation occurs in a subset of c-Fos labeled neurons and is intensity dependent
Negative_regulation (occurs) of Negative_regulation (subset) of c-Fos in neurons associated with nociception and aids-related complex
2) Confidence 0.41 Published 2010 Journal Mol Pain Section Body Doc Link PMC2920254 Disease Relevance 0.94 Pain Relevance 0.21

General Comments

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