INT286397

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.41
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 5
Disease Relevance 0.06
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

vesicle-mediated transport (Mapk8ip3) Golgi apparatus (Mapk8ip3) plasma membrane (Mapk8ip3)
kinase activity (Mapk8ip3) cytoplasm (Mapk8ip3)
Anatomy Link Frequency
eyes 4
Mapk8ip3 (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 10 5.00 Very Low Very Low Very Low
Nerve growth factor 5 5.00 Very Low Very Low Very Low
GABAergic 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Myopia 65 59.20 Quite High
Rigor 5 5.68 Low Low
Death 10 5.00 Very Low Very Low Very Low
Injury 10 5.00 Very Low Very Low Very Low
Ganglion Cysts 10 5.00 Very Low Very Low Very Low
Hyperopia 5 5.00 Very Low Very Low Very Low
Overdose 5 5.00 Very Low Very Low Very Low
Nonsyndromic Deafness 5 5.00 Very Low Very Low Very Low
Adhesions 5 5.00 Very Low Very Low Very Low
Refractive Errors 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Mapk8ip3 (also called Jip3 or JSAP1) mRNA levels were strongly reduced in diffuser-treated eyes.
Negative_regulation (reduced) of Mapk8ip3 in eyes
1) Confidence 0.41 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2774458 Disease Relevance 0 Pain Relevance 0
Mapk8ip3 (also called Jip3 or JSAP1) mRNA levels were strongly reduced in diffuser-treated eyes.
Negative_regulation (reduced) of JSAP1 in eyes
2) Confidence 0.41 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2774458 Disease Relevance 0 Pain Relevance 0
For the purpose of clarity, not all significant changes are shown in Figure 5B but were as follows: the Mapk8ip3 mRNA level was significantly decreased in the treatment groups when compared to the control group (control versus 30 min: p<0.01; control versus 4 h and 6+6 h: p<0.001).


Negative_regulation (decreased) of Mapk8ip3
3) Confidence 0.41 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2774458 Disease Relevance 0 Pain Relevance 0
Other interesting candidates were Akt2, which was up-regulated after 30 min of deprivation and Mapk8ip3, a neuron specific JNK binding and scaffolding protein that was temporally regulated in the diffuser-treated eyes only.


Negative_regulation (deprivation) of Mapk8ip3 in eyes
4) Confidence 0.41 Published 2007 Journal Molecular Vision Section Abstract Doc Link PMC2774458 Disease Relevance 0.06 Pain Relevance 0
Mapk8ip3 (also called Jip3 or JSAP1) mRNA levels were strongly reduced in diffuser-treated eyes.
Negative_regulation (reduced) of Jip3 in eyes
5) Confidence 0.41 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2774458 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox