INT286546

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.27
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.57
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeletal protein binding (Pkd2) transport (Pkd2) endoplasmic reticulum (Pkd2)
plasma membrane (Pkd2) cilium (Pkd2) transmembrane transport (Pkd2)
Pkd2 (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 25 5.00 Very Low Very Low Very Low
ketamine 4 5.00 Very Low Very Low Very Low
Mechanosensation 4 5.00 Very Low Very Low Very Low
Somatostatin 4 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
Cholecystokinin 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 19 88.08 High High
Polycystic Kidney Disease 62 74.64 Quite High
Cystic Kidney Diseases 8 73.52 Quite High
Cyst 32 67.16 Quite High
Apoptosis 17 37.44 Quite Low
Targeted Disruption 9 30.12 Quite Low
Fungal Infection 38 11.04 Low Low
Infection 66 5.00 Very Low Very Low Very Low
Disease 30 5.00 Very Low Very Low Very Low
Sprains And Strains 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, expression of polycystin-2 seems to persist into adult life [62].
Negative_regulation (persist) of Gene_expression (expression) of polycystin-2
1) Confidence 0.27 Published 2007 Journal Cell Mol Life Sci Section Body Doc Link PMC2775119 Disease Relevance 0.57 Pain Relevance 0
As shown in Figure 5B, down-regulation of PKD1 did not affect PKD2 expression (Figure 5B, left panel and Supplementary Figure S4), and only the PKD2.2 siRNA sequence was effective in reducing PKD2 expression (Figure 5B, right panel) without reducing PKD1 levels.
Negative_regulation (reducing) of Gene_expression (expression) of PKD2
2) Confidence 0.15 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3011003 Disease Relevance 0 Pain Relevance 0
At the indicated time points (24, 48 and 72 hrs), 6×106 cells were collected and PKD1, PKD2 and PKD3 protein expression was assayed by Western blotting.
Negative_regulation (assayed) of Gene_expression (expression) of PKD2
3) Confidence 0.15 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3011003 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox