INT286574

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Context Info
Confidence 0.10
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.09
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Pkd1, Cdk2) endosome (Cdk2) Golgi apparatus (Pkd1)
cilium (Pkd1) cytoplasm (Cdk2) cytosol (Cdk2)
Pkd1 (Mus musculus)
Cdk2 (Mus musculus)
Pain Link Frequency Relevance Heat
Mechanosensation 4 5.00 Very Low Very Low Very Low
Somatostatin 4 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Mechanotransduction 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 30 91.28 High High
Polycystic Kidney Disease 62 50.00 Quite Low
Cyst 32 5.00 Very Low Very Low Very Low
Adhesions 19 5.00 Very Low Very Low Very Low
Apoptosis 17 5.00 Very Low Very Low Very Low
Cystic Kidney Diseases 8 5.00 Very Low Very Low Very Low
Congenital Anomalies 6 5.00 Very Low Very Low Very Low
Targeted Disruption 5 5.00 Very Low Very Low Very Low
Syndrome 4 5.00 Very Low Very Low Very Low
Toxicity 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Further analysis has shown that polycystin-1 expression inhibits Cdk2 and induces p21waf1.
Gene_expression (expression) of polycystin-1 Negative_regulation (inhibits) of Cdk2
1) Confidence 0.10 Published 2007 Journal Cell Mol Life Sci Section Body Doc Link PMC2775119 Disease Relevance 0.09 Pain Relevance 0

General Comments

This test has worked.

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