INT286596

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Context Info
Confidence 0.50
First Reported 2009
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 8
Disease Relevance 3.37
Pain Relevance 1.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (SLC9A3R2) nucleus (SLC9A3R2) protein complex assembly (SLC9A3R2)
cytoplasm (SLC9A3R2)
Anatomy Link Frequency
knee 6
SLC9A3R2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 317 94.44 High High
Pain 91 91.76 High High
Pain score 1 58.40 Quite High
palliative 7 36.88 Quite Low
Analgesic 7 5.00 Very Low Very Low Very Low
Inflammation 7 5.00 Very Low Very Low Very Low
Arthritis 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Contracture 35 99.72 Very High Very High Very High
Stress 7 96.08 Very High Very High Very High
Knee Osteoarthritis 280 94.44 High High
Pain 92 91.76 High High
Frailty 60 90.64 High High
Obesity 58 81.32 Quite High
Disease Progression 7 72.92 Quite High
Disease 59 70.32 Quite High
Arthropathy 22 63.08 Quite High
Arthritis 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This suggests small reductions in end-range knee motion may significantly increase one's chance of requiring TKA in the future.
Spec (may) Positive_regulation (increase) of Positive_regulation (requiring) of TKA in knee
1) Confidence 0.50 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2877653 Disease Relevance 0.49 Pain Relevance 0.13
If these are the same clinical predictors that influence the decision to undergo TKA, then patients should be educated to the benefits of undergoing TKA prior to the onset of these severe limitations.
Positive_regulation (educated) of Positive_regulation (undergoing) of TKA
2) Confidence 0.36 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2877653 Disease Relevance 0.38 Pain Relevance 0.21
However, the odds ratio revealed that for a single degree increase in knee flexion contracture, the risk of undergoing TKA increased by 23%.
Positive_regulation (increased) of Positive_regulation (undergoing) of TKA in knee associated with contracture
3) Confidence 0.33 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2877653 Disease Relevance 0.40 Pain Relevance 0.11
The odds ratio revealed that age, extension ROM and KOS-ADLS had a large increase in risk for undergoing TKA with a single unit increase in the variable.
Positive_regulation (increase) of Positive_regulation (undergoing) of TKA
4) Confidence 0.33 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2877653 Disease Relevance 0.42 Pain Relevance 0.11
For every one percentage point decrease in KOS-ADLS score, the chances of undergoing TKA increased by 4%.
Positive_regulation (increased) of Positive_regulation (undergoing) of TKA
5) Confidence 0.33 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2877653 Disease Relevance 0.49 Pain Relevance 0.12
Odds ratio revealed that the risk of undergoing TKA increased by 1.13 times for every year increase in age (Table 3).
Positive_regulation (increased) of Positive_regulation (undergoing) of TKA
6) Confidence 0.33 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2877653 Disease Relevance 0.43 Pain Relevance 0.14
For every degree of knee flexion contracture the chance of undergoing TKA increased by 1.23 times.
Positive_regulation (increased) of Positive_regulation (undergoing) of TKA in knee associated with contracture
7) Confidence 0.33 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2877653 Disease Relevance 0.46 Pain Relevance 0.16
Considering the large and likely increasing population undergoing TKA or THA during the working years, and the beneficial effects associated with returning to work, it is important to understand how best to help these patients return to work after surgery.
Positive_regulation (increasing) of Positive_regulation (undergoing) of TKA
8) Confidence 0.05 Published 2009 Journal J Occup Rehabil Section Body Doc Link PMC2775121 Disease Relevance 0.31 Pain Relevance 0.10

General Comments

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