INT286651

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Context Info
Confidence 0.14
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.50
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (OLR1, PRKCA) nucleoplasm (PRKCA) mitochondrion (PRKCA)
small molecule metabolic process (PRKCA) endoplasmic reticulum (PRKCA) enzyme binding (PRKCA)
OLR1 (Homo sapiens)
PRKCA (Homo sapiens)
Pain Link Frequency Relevance Heat
Angina 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 1 98.98 Very High Very High Very High
Cancer 18 80.88 Quite High
Stress 1 71.68 Quite High
Basal And Squamous Cell Skin Cancer 26 62.24 Quite High
Disease 3 60.08 Quite High
Esophageal Cancer 11 45.20 Quite Low
Hepatocellular Cancer 1 43.52 Quite Low
Cardiovascular Disease 3 35.80 Quite Low
Atherosclerosis 1 29.76 Quite Low
Stomach Cancer 2 7.08 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Low serum levels of the oxLDL antibody can lead to uncontrolled cell proliferation and to the reduction of apoptosis, contributing to the induction of carcinogenesis. oxLDL increases the activity of C protein kinase (PKC), which is a serin-treonin kinase that acts on the cytoplasmatic transduction of the mytogenic signal, induced from GF [43].
oxLDL Positive_regulation (increases) of PKC associated with apoptosis
1) Confidence 0.14 Published 2009 Journal Lipids Health Dis Section Body Doc Link PMC2775732 Disease Relevance 0.50 Pain Relevance 0

General Comments

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