INT286682

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Context Info
Confidence 0.51
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.89
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PLEK) mitochondrion (Maob) extracellular region (PLEK)
oxidoreductase activity (Maob) cytoplasm (PLEK)
Anatomy Link Frequency
platelet 2
Maob (Mus musculus)
PLEK (Homo sapiens)
Pain Link Frequency Relevance Heat
monoamine 6 50.00 Quite Low
addiction 6 5.00 Very Low Very Low Very Low
Serotonin 3 5.00 Very Low Very Low Very Low
sSRI 2 5.00 Very Low Very Low Very Low
Nicotine 2 5.00 Very Low Very Low Very Low
Restless leg syndrome 1 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nicotine Addiction 171 98.78 Very High Very High Very High
Atherosclerosis 3 5.00 Very Low Very Low Very Low
Lung Cancer 3 5.00 Very Low Very Low Very Low
Cancer 3 5.00 Very Low Very Low Very Low
Hypertension 2 5.00 Very Low Very Low Very Low
Obesity 2 5.00 Very Low Very Low Very Low
Cardiovascular Disorder Under Development 2 5.00 Very Low Very Low Very Low
Diabetes Mellitus 2 5.00 Very Low Very Low Very Low
Coronary Artery Disease 2 5.00 Very Low Very Low Very Low
Disorder Of Lipid Metabolism 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This smoking-induced long-lasting effect was due to demethylation of the MAOB gene promoter which resulted in a persistent high protein concentration of platelet MAO-B.
MAOB Positive_regulation (resulted) of Positive_regulation (concentration) of platelet in platelet associated with nicotine addiction
1) Confidence 0.51 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2775922 Disease Relevance 0.89 Pain Relevance 0

General Comments

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