INT286683

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Context Info
Confidence 0.01
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.07
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Gopc, MBD2) transport (Gopc) mRNA binding (MBD2)
Golgi apparatus (Gopc) nucleus (MBD2) plasma membrane (Gopc)
Anatomy Link Frequency
poly 1
Gopc (Mus musculus)
MBD2 (Homo sapiens)
Pain Link Frequency Relevance Heat
antidepressant 1 76.40 Quite High
agonist 1 70.24 Quite High
gABA 1 69.28 Quite High
monoamine 6 50.00 Quite Low
addiction 6 46.32 Quite Low
alcohol 1 45.88 Quite Low
Nicotine 2 45.36 Quite Low
Inflammation 1 20.00 Low Low
Serotonin 3 5.00 Very Low Very Low Very Low
sSRI 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nicotine Addiction 171 100.00 Very High Very High Very High
Suicidal Behaviour 1 89.68 High High
Colon Cancer 1 83.48 Quite High
Anxiety Disorder 1 64.16 Quite High
Cancer 3 54.68 Quite High
Lung Cancer 3 51.16 Quite High
Schizophrenia 1 41.04 Quite Low
Urological Neuroanatomy 1 25.04 Quite Low
INFLAMMATION 1 20.00 Low Low
Disease 1 17.92 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The nucleic acid demethylase activity, possibly due to hyperactive poly(ADP-ribose) polymerases [46], is increased by tobacco smoke (Fig. 4C) and generates aldehydes [24], [47] (Fig. 5) which are able to further cyclize bioamines to generate ?
Fig Positive_regulation (increased) of demethylase in poly associated with nicotine addiction
1) Confidence 0.01 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2775922 Disease Relevance 1.07 Pain Relevance 0.11

General Comments

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