INT286716

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Context Info
Confidence 0.73
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 5
Disease Relevance 1.03
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Musk) plasma membrane (Musk) kinase activity (Musk)
Anatomy Link Frequency
muscle 1
Musk (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 5 70.40 Quite High
Action potential 4 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Congenital Myasthenic Syndromes 88 99.96 Very High Very High Very High
Respiratory Failure 8 98.76 Very High Very High Very High
Metabolic Syndrome 1 93.88 High High
Congenital Anomalies 8 77.36 Quite High
Syndrome 12 37.16 Quite Low
Disease 4 34.28 Quite Low
Muscle Weakness 8 24.80 Low Low
Myasthenia Gravis 12 5.00 Very Low Very Low Very Low
Targeted Disruption 7 5.00 Very Low Very Low Very Low
Ocular Toxicity (including Many Sub-types) 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Finally, despite the fact that Tid1 interacts with the intracellular portion of MuSK, the patient's mutations do not affect the relationship between MuSK and Tid1.
Localization (portion) of MuSK
1) Confidence 0.73 Published 2010 Journal Human Molecular Genetics Section Body Doc Link PMC2876883 Disease Relevance 0.31 Pain Relevance 0.07
-BGT) and the co-localization of the MuSK protein was visualized using a primary antibody directed against the N-terminal of human MuSK.
Localization (localization) of MuSK
2) Confidence 0.73 Published 2010 Journal Human Molecular Genetics Section Body Doc Link PMC2876883 Disease Relevance 0 Pain Relevance 0
Two heteroallelic MUSK mutations were identified in the first reported case of MUSK-associated CMS (5).
Localization (case) of MUSK associated with congenital myasthenic syndromes
3) Confidence 0.64 Published 2010 Journal Human Molecular Genetics Section Body Doc Link PMC2876883 Disease Relevance 0.31 Pain Relevance 0
Two heteroallelic MUSK mutations were identified in the first reported case of MUSK-associated CMS (5).
Localization (case) of MUSK-associated associated with congenital myasthenic syndromes
4) Confidence 0.64 Published 2010 Journal Human Molecular Genetics Section Body Doc Link PMC2876883 Disease Relevance 0.31 Pain Relevance 0
Using muscle-specific gene deletion in mice, we now show that p38?
Localization (deletion) of muscle-specific in muscle
5) Confidence 0.05 Published 2009 Journal PLoS ONE Section Abstract Doc Link PMC2775956 Disease Relevance 0.09 Pain Relevance 0

General Comments

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