INT286753

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Context Info
Confidence 0.09
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.82
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Apaf1) Golgi apparatus (Apaf1) nucleus (Apaf1)
intracellular (Apaf1) cytoplasm (Apaf1)
Apaf1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 32 86.40 High High
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 2 99.96 Very High Very High Very High
Cancer 142 96.72 Very High Very High Very High
Non-small-cell Lung Cancer 2 93.68 High High
Autoimmune Disease 6 88.64 High High
INFLAMMATION 32 86.40 High High
Metastasis 2 79.68 Quite High
Lung Cancer 186 77.04 Quite High
Malignant Neoplastic Disease 16 5.00 Very Low Very Low Very Low
Hypoxia 8 5.00 Very Low Very Low Very Low
Targeted Disruption 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effect of TUSC2 on chemosensitivity was associated with down-regulation of MDM2, accumulation of p53, and activation of the Apaf-1 apoptotic pathway [22].
Negative_regulation (down) of Positive_regulation (activation) of Apaf-1 associated with apoptosis
1) Confidence 0.09 Published 2009 Journal Mol Cancer Section Body Doc Link PMC2776015 Disease Relevance 1.41 Pain Relevance 0.15
The effect of TUSC2 on chemosensitivity was associated with down-regulation of MDM2, accumulation of p53, and activation of the Apaf-1 apoptotic pathway [22].
Negative_regulation (regulation) of Positive_regulation (activation) of Apaf-1 associated with apoptosis
2) Confidence 0.09 Published 2009 Journal Mol Cancer Section Body Doc Link PMC2776015 Disease Relevance 1.41 Pain Relevance 0.15

General Comments

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