INT286771

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Context Info
Confidence 0.01
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.66
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ros1) cell proliferation (Ros1) signal transduction (Ros1)
plasma membrane (Ros1) molecular_function (Tusc2) cellular_component (Tusc2)
Ros1 (Mus musculus)
Tusc2 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 16 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Lung Cancer 93 94.08 High High
Malignant Neoplastic Disease 8 83.72 Quite High
Cancer 71 75.08 Quite High
INFLAMMATION 16 5.00 Very Low Very Low Very Low
Hypoxia 4 5.00 Very Low Very Low Very Low
Autoimmune Disease 3 5.00 Very Low Very Low Very Low
Targeted Disruption 3 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Systemic Lupus Erythematosus 2 5.00 Very Low Very Low Very Low
Hyperplasia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
AI designed the study, participated in its coordination, carried out the molecular studies on asbestos and ROS effects on TUSC2 expression, was involved in the analysis of microarray data and their molecular confirmation, processed all the data and wrote the manuscript, SI carried out mesothelioma genomic and transcriptomic database analyses, was involved in molecular experimentations and helped to draft two chapters of the manuscript, LP performed the analysis and scoring of immunostained mesothelioma tissues, DN performed the analysis and scoring of immunostained mesothelioma tissues independently of LP, AT performed an initial analysis of stained mesothelioma samples, IW coordinated the mesothelioma tissue acquisition and staining from MD Anderson Cancer Center site and participated in preparation of Methods section and discussion of the results, ZL performed the analysis of microarray data, JR participated in discussion of the data and the manuscript, HP conceived of the study, and participated in its design and coordination and was involved in tissue acquisition and collection of patients' clinical data.
ROS Regulation (effects) of Gene_expression (expression) of TUSC2 associated with lung cancer and cancer
1) Confidence 0.01 Published 2009 Journal Mol Cancer Section Body Doc Link PMC2776015 Disease Relevance 0.66 Pain Relevance 0

General Comments

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