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Context Info
Confidence 0.49
First Reported 1984
Last Reported 1989
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 2.92
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (CIC) DNA binding (CIC)
Anatomy Link Frequency
B cells 1
CIC (Homo sapiens)
Pain Link Frequency Relevance Heat
Arthritis 2 94.08 High High
Angina 3 93.84 High High
spinal inflammation 2 75.00 Quite High
psoriasis 1 59.92 Quite High
Disease Link Frequency Relevance Heat
Reprotox - General 2 1 97.56 Very High Very High Very High
Arthralgia 1 96.68 Very High Very High Very High
Myalgia 1 96.20 Very High Very High Very High
Syndrome 10 95.36 Very High Very High Very High
Arthritis 2 94.08 High High
Coronary Artery Disease 5 94.00 High High
Cv General 3 Under Development 3 93.84 High High
Chronic Hepatitis 1 90.08 High High
Arthropathy 2 89.92 High High
Yang Deficiency 1 89.56 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Total haemolytic complement activity in serum was negatively correlated with concentrations of CIC or CRP indicating complement activation in patients with such complexes.
Positive_regulation (concentrations) of CIC
1) Confidence 0.49 Published 1984 Journal Clin. Rheumatol. Section Abstract Doc Link 6335423 Disease Relevance 0.88 Pain Relevance 0.26
After treatment with both powder of Kuo Guan No 1 and Kuo Guan No 2, the increased levels of IgG, CIC, IC-IgG and IC-C3 in serum and the numbers of B cells in peripheral blood lymphocyte (PBL) of the patients with Ben-Xu Biao-Shi (BXBS, ) syndrome of IHD angina were markedly decreased and showed no significant difference while compared with the normal controls (P greater than 0.05); the numbers of OKT+3, OKT+4 and OKT+8 cells in PBL, which were lower before treatment in both groups, were obviously increased and showed no marked difference with the controls (P greater than 0.05); the higher ratio of T4/T8 was lowered in group of YXXY syndrome, and showed no difference while compared with the controls (P greater than 0.05), but the ratio in QYXXY syndrome group was lowered than that in the controls (P less than 0.05).
Positive_regulation (increased) of CIC in B cells associated with angina, coronary artery disease and syndrome
2) Confidence 0.45 Published 1989 Journal Zhong Xi Yi Jie He Za Zhi Section Abstract Doc Link 2788037 Disease Relevance 1.02 Pain Relevance 0.09
The normalization of increased ristomycin-cofactor activity of Willebrand factor and CIC levels was noted in one case.
Positive_regulation (increased) of CIC
3) Confidence 0.45 Published 1987 Journal Ter. Arkh. Section Abstract Doc Link 2957814 Disease Relevance 1.02 Pain Relevance 0.08

General Comments

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