INT286987

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Context Info
Confidence 0.23
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.91
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (ERBB2) signal transduction (ERBB2) plasma membrane (ERBB2)
nucleus (ERBB2) cytoplasm (ERBB2)
ERBB2 (Homo sapiens)
Pain Link Frequency Relevance Heat
addiction 5 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 133 84.80 Quite High
Apoptosis 28 83.20 Quite High
Death 5 64.96 Quite High
Prostate Cancer 27 50.00 Quite Low
Bladder Cancer 24 50.00 Quite Low
Hyperplasia 1 37.36 Quite Low
Vomiting 1 17.12 Low Low
Diarrhoea 1 16.64 Low Low
Weight Loss 1 16.24 Low Low
Toxicity 3 15.04 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Increased phosphorylation of ErbB2(Thr686), ErbB2(Ser1113) and limited phosphorylation of EGFR(Thy845), ErbB2(Tyr1221/1222), ErbB3(Tyr1289) and ErbB4(Tyr1284) sites was seen in the control group.
Positive_regulation (Increased) of Phosphorylation (phosphorylation) of ErbB2
1) Confidence 0.23 Published 2009 Journal Mol Cancer Section Body Doc Link PMC2777152 Disease Relevance 0.91 Pain Relevance 0
The addition of DHT to C-33 cells decreased PAcP expression and increased Her2 phosphorylation (Fig. 3A).
Positive_regulation (increased) of Phosphorylation (phosphorylation) of Her2
2) Confidence 0.20 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2812491 Disease Relevance 0 Pain Relevance 0

General Comments

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