INT287072

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Context Info
Confidence 0.18
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.06
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Chrm2) nucleus (Irf4) plasma membrane (Chrm2)
DNA binding (Irf4) cytoplasm (Irf4) signal transducer activity (Chrm2)
Chrm2 (Mus musculus)
Irf4 (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 1 63.52 Quite High
Epstein-barr Virus 15 43.28 Quite Low
Lymphatic System Cancer 12 30.32 Quite Low
Infection 29 5.00 Very Low Very Low Very Low
Sarcoma 2 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low
Viral Infection 2 5.00 Very Low Very Low Very Low
Sleep Disorders 1 5.00 Very Low Very Low Very Low
Lymphoproliferative Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Finally, as we have shown here, M2 also upregulates the expression of IRF4 [we have observed both M2-driven upregulation of IRF4 transcripts (Fig. 6C) and IRF4 protein (data not shown) in BCL-1 cells].
M2 Positive_regulation (upregulates) of Gene_expression (expression) of IRF4
1) Confidence 0.18 Published 2009 Journal PLoS Pathogens Section Body Doc Link PMC2777334 Disease Relevance 0.06 Pain Relevance 0

General Comments

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