INT287087

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Context Info
Confidence 0.61
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.60
Pain Relevance 0.72

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
enteroendocrine cell 1
Pelvis 1
EEC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Serotonin 2 100.00 Very High Very High Very High
imagery 15 99.92 Very High Very High Very High
spastic colon 57 77.68 Quite High
Crohn's disease 1 48.28 Quite Low
Piles 1 39.84 Quite Low
Inflammation 15 39.32 Quite Low
alcohol 1 38.04 Quite Low
Eae 3 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress Incontinence 37 100.00 Very High Very High Very High
Infection 17 99.76 Very High Very High Very High
Chlamydia Infection 57 97.20 Very High Very High Very High
Syndrome 2 78.76 Quite High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

54 77.68 Quite High
Gastroenteritis 4 74.48 Quite High
Bladder Exstrophy 44 53.28 Quite High
Disease 8 52.76 Quite High
Epispadias 17 50.00 Quite Low
Inflammatory Bowel Disease 1 49.16 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
a) Pelvis and pelvic floor in EEC
Localization (floor) of EEC in Pelvis associated with stress incontinence
1) Confidence 0.61 Published 2009 Journal Orphanet J Rare Dis Section Body Doc Link PMC2777855 Disease Relevance 0.28 Pain Relevance 0.19
Infection may impair EEC serotonin and hormone secretion and cause motility disturbances but further studies on enteroendocrine cell lines or cultured EEC are required for elucidating such a mechanism.


Localization (secretion) of EEC in enteroendocrine cell associated with serotonin and infection
2) Confidence 0.10 Published 2010 Journal BMC Gastroenterol Section Body Doc Link PMC2834606 Disease Relevance 0.88 Pain Relevance 0.53

General Comments

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