INT287091

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Context Info
Confidence 0.31
First Reported 2009
Last Reported 2009
Negated 1
Speculated 1
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 2.81
Pain Relevance 1.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
dorsal horn 2
FL (Mus musculus)
Pain Link Frequency Relevance Heat
spinal dorsal horn 15 99.88 Very High Very High Very High
Inflammation 33 98.92 Very High Very High Very High
Root ganglion neuron 6 98.80 Very High Very High Very High
Neuropathic pain 12 93.76 High High
Thermal hyperalgesia 3 72.20 Quite High
intrathecal 6 68.28 Quite High
Pain 27 49.96 Quite Low
qutenza 30 39.84 Quite Low
nociceptor 3 32.16 Quite Low
agonist 3 29.24 Quite Low
Disease Link Frequency Relevance Heat
INFLAMMATION 36 98.92 Very High Very High Very High
Ganglion Cysts 6 98.48 Very High Very High Very High
Targeted Disruption 18 97.00 Very High Very High Very High
Neuropathic Pain 21 93.76 High High
Acquired Immune Deficiency Syndrome Or Hiv Infection 9 92.64 High High
Nociception 39 90.84 High High
Hyperalgesia 9 72.20 Quite High
Nervous System Injury 6 71.04 Quite High
Hypersensitivity 42 61.48 Quite High
Pain 33 49.96 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As demonstrated in Additional File 1, we detected no significant regulation of trkB.FL mRNA (panels A-D) following antiretroviral or inflammatory treatment compared with vehicle controls in either genotype.
Neg (no) Regulation (regulation) of FL associated with inflammation
1) Confidence 0.31 Published 2009 Journal Mol Pain Section Body Doc Link PMC2777863 Disease Relevance 0.85 Pain Relevance 0.41
Since trkB.T1 and trkB.FL are presumably regulated by a common promoter, we also undertook a careful examination of spinal dorsal horn trkB.FL mRNA and protein regulation in the antiretroviral and inflammatory models in both wildtype and trkB.T1 knockout animals.
Regulation (regulated) of FL in dorsal horn associated with targeted disruption, inflammation and spinal dorsal horn
2) Confidence 0.14 Published 2009 Journal Mol Pain Section Body Doc Link PMC2777863 Disease Relevance 1.02 Pain Relevance 0.38
Since trkB.T1 and trkB.FL are presumably regulated by a common promoter, we also undertook a careful examination of spinal dorsal horn trkB.FL mRNA and protein regulation in the antiretroviral and inflammatory models in both wildtype and trkB.T1 knockout animals.
Spec (examination) Regulation (regulation) of FL in dorsal horn associated with targeted disruption, inflammation and spinal dorsal horn
3) Confidence 0.14 Published 2009 Journal Mol Pain Section Body Doc Link PMC2777863 Disease Relevance 0.94 Pain Relevance 0.38

General Comments

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