INT287095

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Context Info
Confidence 0.24
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.47
Pain Relevance 0.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (T) DNA binding (T) cytoplasm (T)
Anatomy Link Frequency
neurons 2
T (Mus musculus)
Pain Link Frequency Relevance Heat
induced neuropathy 1 91.28 High High
intrathecal 2 89.68 High High
Pain 9 80.80 Quite High
Dorsal horn 4 72.52 Quite High
Lasting pain 2 49.84 Quite Low
qutenza 10 24.44 Low Low
Inflammation 11 23.20 Low Low
spinal dorsal horn 5 7.84 Low Low
withdrawal 5 5.00 Very Low Very Low Very Low
Neuropathic pain 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neuropathic Pain 7 90.64 High High
Hypersensitivity 14 80.96 Quite High
Pain 11 80.80 Quite High
Nociception 13 26.56 Quite Low
INFLAMMATION 12 23.20 Low Low
Sprains And Strains 1 19.08 Low Low
Targeted Disruption 6 5.00 Very Low Very Low Very Low
Hyperalgesia 3 5.00 Very Low Very Low Very Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 3 5.00 Very Low Very Low Very Low
Ganglion Cysts 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We have shown that neurons from a mouse model of neurodegeneration over-express trkB.T1, resulting in a significant increase in resting intracellular calcium; reducing trkB.T1 expression in those neurons reduced intracellular calcium to wildtype levels [23].
Negative_regulation (reducing) of Gene_expression (expression) of T1 in neurons
1) Confidence 0.24 Published 2009 Journal Mol Pain Section Body Doc Link PMC2777863 Disease Relevance 0.47 Pain Relevance 0.41

General Comments

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