INT287098

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Context Info
Confidence 0.10
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.66
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (T) DNA binding (T) cytoplasm (T)
FL (Mus musculus)
T (Mus musculus)
Pain Link Frequency Relevance Heat
Hyperalgesia 2 66.24 Quite High
medulla 1 64.92 Quite High
spinal dorsal horn 5 64.12 Quite High
Pain 9 52.92 Quite High
Root ganglion neuron 2 33.44 Quite Low
Neuropathic pain 4 28.80 Quite Low
Inflammation 11 5.00 Very Low Very Low Very Low
qutenza 10 5.00 Very Low Very Low Very Low
withdrawal 5 5.00 Very Low Very Low Very Low
Dorsal horn 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypersensitivity 14 79.44 Quite High
Nervous System Injury 2 77.52 Quite High
Targeted Disruption 6 74.60 Quite High
Disease 1 73.52 Quite High
Death 1 67.52 Quite High
Hyperalgesia 3 66.24 Quite High
Down Syndrome 1 65.44 Quite High
Nociception 13 56.44 Quite High
Pain 11 52.92 Quite High
Ganglion Cysts 2 33.04 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since trkB.T1 heterodimerization with trkB.FL inhibits trans-autophosphorylation of the trkB.FL kinase domain, studies support a model in which trkB.T1 functions to reduce BDNF signaling [17-22].
FL Binding (heterodimerization) of T1
1) Confidence 0.10 Published 2009 Journal Mol Pain Section Body Doc Link PMC2777863 Disease Relevance 0.66 Pain Relevance 0.23

General Comments

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