INT287100

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Context Info
Confidence 0.30
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.61
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ntrk2) cytosol (Ntrk2) plasma membrane (Ntrk2)
kinase activity (Ntrk2)
FL (Mus musculus)
Ntrk2 (Mus musculus)
Pain Link Frequency Relevance Heat
Lasting pain 2 90.72 High High
intrathecal 2 70.64 Quite High
induced neuropathy 1 70.12 Quite High
Pain 9 44.76 Quite Low
Dorsal horn 4 36.48 Quite Low
Inflammation 11 5.00 Very Low Very Low Very Low
qutenza 10 5.00 Very Low Very Low Very Low
spinal dorsal horn 5 5.00 Very Low Very Low Very Low
withdrawal 5 5.00 Very Low Very Low Very Low
Neuropathic pain 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Nociception 13 99.44 Very High Very High Very High
Hypersensitivity 14 95.72 Very High Very High Very High
Pain 11 90.72 High High
Neuropathic Pain 7 70.12 Quite High
Targeted Disruption 6 9.52 Low Low
INFLAMMATION 12 5.00 Very Low Very Low Very Low
Hyperalgesia 3 5.00 Very Low Very Low Very Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 3 5.00 Very Low Very Low Very Low
Ganglion Cysts 2 5.00 Very Low Very Low Very Low
Nervous System Injury 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, we conclude that while previous studies have demonstrated a specific role for BDNF-mediated trkB.FL signaling in nociception, our results support a role for trkB.T1 in nociception that has not been previously described.


FL Positive_regulation (role) of trkB associated with nociception
1) Confidence 0.30 Published 2009 Journal Mol Pain Section Body Doc Link PMC2777863 Disease Relevance 0.61 Pain Relevance 0.20

General Comments

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