INT28711

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Context Info
Confidence 0.23
First Reported 1989
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.96
Pain Relevance 0.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (HLA-B, MRAP) endoplasmic reticulum (MRAP) cytoplasm (MRAP)
HLA-B (Homo sapiens)
MRAP (Homo sapiens)
Pain Link Frequency Relevance Heat
spinal inflammation 10 99.44 Very High Very High Very High
Disease Link Frequency Relevance Heat
Disease 4 100.00 Very High Very High Very High
Low Back Pain 10 99.44 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Several hypotheses, each based on a particular feature of HLA-B27, guide much of the current research on the pathogenesis of this disease, but none has yet satisfactorily explained its mechanism and the differential association of B27 subtypes to it.
HLA-B27 Binding (association) of B27 associated with disease
1) Confidence 0.23 Published 2008 Journal Tissue Antigens Section Abstract Doc Link 18489433 Disease Relevance 0.37 Pain Relevance 0.09
We examined the distribution of non-B27 alleles of the HLA-B locus among B27+ patients with ankylosing spondylitis (AS), to detect any additional HLA-B locus allele(s) that may act in conjunction with B27 to increase susceptibility to AS.
HLA-B Binding (conjunction) of B27 associated with spinal inflammation
2) Confidence 0.04 Published 1989 Journal Arthritis Rheum. Section Abstract Doc Link 2789045 Disease Relevance 0.59 Pain Relevance 0.59

General Comments

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