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Context Info
Confidence 0.11
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.64
Pain Relevance 0.76

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (NT5E) plasma membrane (NT5E) DNA metabolic process (NT5E)
cytoplasm (NT5E)
Anatomy Link Frequency
small intestine 1
NT5E (Homo sapiens)
Pain Link Frequency Relevance Heat
adenocard 33 96.72 Very High Very High Very High
Catechol-O-methyltransferase 58 95.24 Very High Very High Very High
Kinase C 4 91.08 High High
Dopamine 19 86.92 High High
ischemia 32 79.60 Quite High
Inflammation 1 53.28 Quite High
Bioavailability 6 32.24 Quite Low
anesthesia 2 19.12 Low Low
agonist 5 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 1 85.48 High High
Myocardial Infarction 12 84.72 Quite High
Parkinson's Disease 1 84.60 Quite High
Cv Unclassified Under Development 31 79.60 Quite High
Reperfusion Injury 5 63.32 Quite High
INFLAMMATION 1 53.28 Quite High
Disease 44 50.00 Quite Low
Injury 3 50.00 Quite Low
Hyperemia 10 5.00 Very Low Very Low Very Low
Cognitive Disorder 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, inhibition of ATP degradation via targeted gene deletion or inhibition of CD39 and CD73 has been found to eliminate the cardioprotective effect of preconditioning [32], and increase infarct size [33].
Protein_catabolism (degradation) of CD73
1) Confidence 0.11 Published 2010 Journal BMC Cardiovasc Disord Section Body Doc Link PMC2820435 Disease Relevance 0.64 Pain Relevance 0.47
During LD/CD/EN
               administration, LD is mainly degraded to the tyrosine aminotransferase-dependent
               substrates dihydroxyphenylpyruvate acetate and trihydroxyphenylacetate and to a
               distinctly lesser extent to dihydroxyphenylacetic acid in the periphery.33 This more basic milieu may
               hypothetically influence the activity of the intestinal
               H+-coupled nutrient, micronutrient and drug transporters in
               the mammalian small intestine and thus enable a better transport of acids into the
               peripheral blood circulation.26,31,32 Previous studies showed no effect
               of acute COMT inhibition with EN on gastric emptying. 
Protein_catabolism (degraded) of EN in small intestine associated with catechol-o-methyltransferase
2) Confidence 0.07 Published 2009 Journal Patient Prefer Adherence Section Body Doc Link PMC2778405 Disease Relevance 0 Pain Relevance 0.28

General Comments

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