INT287174

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Context Info
Confidence 0.18
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.11
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (PGR) enzyme binding (PGR) DNA binding (PGR)
cell-cell signaling (PGR) cytoplasm (PGR) signal transduction (PGR)
Anatomy Link Frequency
hypothalamus 2
PGR (Homo sapiens)
SHBG (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 8 77.04 Quite High
withdrawal 16 5.00 Very Low Very Low Very Low
Dismenorea 14 5.00 Very Low Very Low Very Low
cva 14 5.00 Very Low Very Low Very Low
endometriosis 6 5.00 Very Low Very Low Very Low
nud 6 5.00 Very Low Very Low Very Low
antagonist 6 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Migraine 2 5.00 Very Low Very Low Very Low
pain pelvic 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Confusion 2 53.48 Quite High
Hemorrhage 104 5.00 Very Low Very Low Very Low
Reprotox - General 1 60 5.00 Very Low Very Low Very Low
Cv General 3 Under Development 14 5.00 Very Low Very Low Very Low
Reprotox - General 2 10 5.00 Very Low Very Low Very Low
Dysmenorrhea 6 5.00 Very Low Very Low Very Low
Dyspepsia 6 5.00 Very Low Very Low Very Low
Reprotox - General 3 6 5.00 Very Low Very Low Very Low
Emergencies 4 5.00 Very Low Very Low Very Low
Pressure Volume 2 Under Development 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Its LD50i is >5000 mg/kg.14 When circulating, 47.5% is bound to sex hormone binding globulin (SHBG), 50% to albumin, while 2.5% is unbound.15 When bound to progesterone receptor in the hypothalamus, levonorgestrel is capable of slowing gonadotropin releasing hormone (GnRH) pulse release, quenching the pre-ovulatory luteinizing hormone (LH) surge.
progesterone receptor Binding (bound) of SHBG in hypothalamus
1) Confidence 0.18 Published 2009 Journal Patient Prefer Adherence Section Body Doc Link PMC2778424 Disease Relevance 0.05 Pain Relevance 0.04
Its LD50i is >5000 mg/kg.14 When circulating, 47.5% is bound to sex hormone binding globulin (SHBG), 50% to albumin, while 2.5% is unbound.15 When bound to progesterone receptor in the hypothalamus, levonorgestrel is capable of slowing gonadotropin releasing hormone (GnRH) pulse release, quenching the pre-ovulatory luteinizing hormone (LH) surge.
progesterone receptor Binding (bound) of hormone binding globulin in hypothalamus
2) Confidence 0.16 Published 2009 Journal Patient Prefer Adherence Section Body Doc Link PMC2778424 Disease Relevance 0.05 Pain Relevance 0.04

General Comments

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