INT287223

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Context Info
Confidence 0.03
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.56
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Pdx1) endoplasmic reticulum (Insig1) nucleus (Pdx1)
DNA binding (Pdx1) transcription factor binding (Pdx1) lipid metabolic process (Insig1)
Pdx1 (Mus musculus)
Insig1 (Mus musculus)
Pain Link Frequency Relevance Heat
Somatostatin 1 91.96 High High
cytokine 1 27.84 Quite Low
Central nervous system 4 5.00 Very Low Very Low Very Low
medulla 4 5.00 Very Low Very Low Very Low
corticosteroid 1 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Bile 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 24 86.28 High High
Diabetes Mellitus 2 79.12 Quite High
Disease 86 68.60 Quite High
Myocardial Infarction 2 60.76 Quite High
Alzheimer's Dementia 2 47.08 Quite Low
Death 1 38.12 Quite Low
Frailty 12 35.16 Quite Low
Weight Loss 9 5.00 Very Low Very Low Very Low
Obesity 6 5.00 Very Low Very Low Very Low
Muscle Disease 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
R6/2 mice develop an age-dependent reduction in insulin mRNA production and diminished expression of key regulators of insulin gene transcription: PDX-1, E2A, CBP, and p300 [46].
PDX-1 Regulation (regulators) of Transcription (transcription) of insulin gene
1) Confidence 0.03 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2778556 Disease Relevance 0.56 Pain Relevance 0.05

General Comments

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