INT287233

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Context Info
Confidence 0.07
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.12
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (PDLIM7, BMP2) cell differentiation (PDLIM7) extracellular space (BMP2)
growth (BMP2) extracellular region (BMP2) embryo development (BMP2)
PDLIM7 (Homo sapiens)
BMP2 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 4 60.96 Quite High
cytokine 5 30.64 Quite Low
Facet joint 19 5.00 Very Low Very Low Very Low
imagery 13 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Nicotine 2 5.00 Very Low Very Low Very Low
Osteoarthritis 2 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
nociceptor 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Intervertebral Disk Degeneration 34 68.80 Quite High
Disease 4 52.56 Quite High
Osteoarthritis 8 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Apoptosis 3 5.00 Very Low Very Low Very Low
Aging 3 5.00 Very Low Very Low Very Low
Injury 3 5.00 Very Low Very Low Very Low
Cadaver 2 5.00 Very Low Very Low Very Low
Sclerosis 2 5.00 Very Low Very Low Very Low
Cytomegalovirus Infection 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Based on these findings, the authors suggested that LMP-1 upregulates the gene expression of BMP-2 and BMP-7 and that the increased level of BMP production resulted in an increased PG synthesis.
LMP-1 Positive_regulation (upregulates) of Gene_expression (expression) of BMP-2
1) Confidence 0.07 Published 2006 Journal J Orthop Sci Section Body Doc Link PMC2778630 Disease Relevance 0.12 Pain Relevance 0.03

General Comments

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