INT287307

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Context Info
Confidence 0.48
First Reported 2008
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 9
Total Number 10
Disease Relevance 11.24
Pain Relevance 2.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (ENO1) lyase activity (ENO1) carbohydrate metabolic process (ENO1)
DNA binding (ENO1) cytoplasm (ENO1) cytosol (ENO1)
Anatomy Link Frequency
blood 2
artery 1
nucleus 1
ENO1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Piles 345 100.00 Very High Very High Very High
cva 317 100.00 Very High Very High Very High
Acute pain 3 89.92 High High
Perioperative pain 9 88.56 High High
Pain 53 80.00 Quite High
Lasting pain 27 54.24 Quite High
Prostatitis 3 49.20 Quite Low
Bile 3 47.28 Quite Low
Inflammation 3 37.44 Quite Low
analgesia 4 36.68 Quite Low
Disease Link Frequency Relevance Heat
Anorectal Disorders 345 100.00 Very High Very High Very High
Cv General 3 Under Development 216 100.00 Very High Very High Very High
Post-partum Hemorrhage 72 100.00 Very High Very High Very High
Shock 28 99.80 Very High Very High Very High
Pressure Volume 2 Under Development 230 98.64 Very High Very High Very High
Placenta Accreta 6 98.48 Very High Very High Very High
Lacerations 14 97.64 Very High Very High Very High
Hernia 24 97.24 Very High Very High Very High
Syndrome 21 97.16 Very High Very High Very High
Failure To Thrive 4 96.64 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The only study published to date which specifically examines an association between PPH and breastfeeding is a small case series describing insufficient milk syndrome and failure to thrive in infants associated with maternal PPH [6].
PPH Binding (association) of associated with failure to thrive, syndrome and cva
1) Confidence 0.48 Published 2010 Journal Int Breastfeed J Section Body Doc Link PMC2889881 Disease Relevance 1.30 Pain Relevance 0.26
Firstly, it was not designed to establish causal associations between the PPH and breastfeeding outcomes.
PPH Binding (associations) of associated with cva
2) Confidence 0.42 Published 2010 Journal Int Breastfeed J Section Body Doc Link PMC2889881 Disease Relevance 0.34 Pain Relevance 0.09
Reasons for admission to either HDU or ICU were not well reported, but for those 16 women where a reason was recorded all related to complications associated with the PPH.


PPH Binding (associated) of associated with cva
3) Confidence 0.42 Published 2010 Journal Int Breastfeed J Section Body Doc Link PMC2889881 Disease Relevance 0.37 Pain Relevance 0.10
Instead, Aigner et al. demonstrated with anatomical dissections that neither PPH nor Doppler ligation completely interrupt the superior rectal artery branches, and of course there is still the vascular supply from below [41].


PPH Neg (neither) Binding (ligation) of in artery associated with piles
4) Confidence 0.41 Published 2008 Journal Tech Coloproctol Section Body Doc Link PMC2778725 Disease Relevance 1.95 Pain Relevance 0.82
New trends for PPH
PPH Binding (trends) of associated with piles
5) Confidence 0.36 Published 2008 Journal Tech Coloproctol Section Body Doc Link PMC2778725 Disease Relevance 1.59 Pain Relevance 0.35
For example, in one woman's words:

"...now it's bothering me that the doctors in hospital would just not listen to me about getting a blood transfusion earlier (I had a PPH previously with my first child) and my recovery and difficulties with breast feeding would have been so much better!"

PPH Binding (had) of in blood associated with cva
6) Confidence 0.32 Published 2010 Journal Int Breastfeed J Section Body Doc Link PMC2889881 Disease Relevance 0.69 Pain Relevance 0.13
To be eligible for the study, women presented with PPH and shock, defined by an initial blood loss of ?
PPH Binding (presented) of in blood associated with pressure volume 2 under development, shock and cva
7) Confidence 0.32 Published 2010 Journal Reprod Health Section Body Doc Link PMC2942803 Disease Relevance 1.53 Pain Relevance 0.31
Tenesmus affected 50% of the patients who underwent PPH for fourth-degree hemorrhoids one year after surgery in a prospective randomized trial that compared stapled hemorrhoidopexy with manual hemorrhoidectomy [19].
PPH Binding (underwent) of associated with piles
8) Confidence 0.32 Published 2008 Journal Tech Coloproctol Section Body Doc Link PMC2778725 Disease Relevance 1.35 Pain Relevance 0.36
PPH, a life-threatening condition globally, is associated with 25% of maternal deaths [1].
PPH Binding (associated) of associated with cva
9) Confidence 0.27 Published 2010 Journal Reprod Health Section Body Doc Link PMC2942803 Disease Relevance 0.85 Pain Relevance 0.10
This activated form of Notch1 then translocates to the nucleus and binds with the DNA-binding protein complex CSL (C promoter-binding factor 1, suppressor of hairless and Lag-1), resulting in transactivation of various target genes like hairy enhancer of split-1 (HES-1).
promoter-binding factor 1 Binding (binding) of in nucleus
10) Confidence 0.03 Published 2009 Journal Journal of Oncology Section Body Doc Link PMC2798103 Disease Relevance 1.27 Pain Relevance 0

General Comments

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