INT287383

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.06
First Reported 2009
Last Reported 2009
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 7
Disease Relevance 3.24
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
eyes 5
amacrine cells 1
Nstr2 (Mus musculus)
Pain Link Frequency Relevance Heat
gABA 7 69.28 Quite High
tetrodotoxin 7 68.36 Quite High
ischemia 7 57.76 Quite High
ketamine 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Optic Nerve Injuries 441 99.54 Very High Very High Very High
Sprains And Strains 14 91.36 High High
Ganglion Cysts 14 73.04 Quite High
Injury 56 60.00 Quite High
Cv Unclassified Under Development 7 57.76 Quite High
Ocular Hypertension 21 53.68 Quite High
Death 28 30.80 Quite Low
Eye Disease 7 25.68 Quite Low
Targeted Disruption 7 5.00 Very Low Very Low Very Low
Disease 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
At this point after ONT, the reduced pSTR and nSTR responses from operated eyes amounted to approximately 55% of those values recorded for the unoperated eyes (t-test, p<0.001), while no other apparent differences in ERG scotopic and mixed responses were observed between operated and unoperated eyes.
Regulation (responses) of nSTR in eyes associated with optic nerve injuries
1) Confidence 0.06 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2779069 Disease Relevance 0.48 Pain Relevance 0
At this point after ONT, the reduced pSTR and nSTR responses from operated eyes were approximately 60% of those values recorded for the unoperated eyes (t-test, p<0.001), while no other apparent differences in ERG scotopic and mixed responses were observed between operated and unoperated eyes.
Regulation (responses) of nSTR in eyes associated with optic nerve injuries
2) Confidence 0.06 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2779069 Disease Relevance 0.49 Pain Relevance 0
ERG studies performed in cats [4], pigmented rats [7], pigmented mice [8,9], monkeys [10], and humans [11] indicate that the RGC population is responsible at least in part for the generation of the pSTR and nSTR responses, although these STR responses may also contain a contribution of amacrine cells [8,9,11].
Regulation (responses) of nSTR in amacrine cells
3) Confidence 0.06 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2779069 Disease Relevance 0.24 Pain Relevance 0.03
Figure 5A shows the ERG traces from a single representative animal of group III illustrating the reductions in the pSTR and nSTR responses of approximately 40% in the operated eyes versus unoperated eyes (t-test, p<0.001).
Regulation (responses) of nSTR in eyes
4) Confidence 0.05 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2779069 Disease Relevance 0.38 Pain Relevance 0
ERG traces from albino animals in group I (n=6) examined one week after ONT showed reductions in the pSTR and nSTR responses of approximately 40% when compared to the unoperated contralateral eye (t-test, p<0.001).
Regulation (responses) of nSTR in eye associated with optic nerve injuries
5) Confidence 0.05 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2779069 Disease Relevance 0.50 Pain Relevance 0
The pSTR and nSTR responses at 12 weeks, the longest time examined, were comparable in the pigmented and the albino rats (Figure 9).
Spec (examined) Regulation (responses) of nSTR
6) Confidence 0.05 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2779069 Disease Relevance 0.72 Pain Relevance 0.10
Figure 5B shows the ERG traces from a single representative animal of group VII illustrating the reductions in the pSTR and nSTR responses of approximately 60% in the operated eyes versus unoperated eyes (t-test, p<0.001).
Regulation (responses) of nSTR in eyes
7) Confidence 0.05 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2779069 Disease Relevance 0.42 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox