INT287442

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Context Info
Confidence 0.47
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 9
Disease Relevance 2.64
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Optn) cytoplasmic membrane-bounded vesicle (Optn) cytoplasm (Optn)
Anatomy Link Frequency
bladders 3
Optn (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Hippocampus 9 78.48 Quite High
Central nervous system 18 65.12 Quite High
Inflammation 18 8.32 Low Low
anesthesia 18 5.00 Very Low Very Low Very Low
ketamine 9 5.00 Very Low Very Low Very Low
Nerve growth factor 9 5.00 Very Low Very Low Very Low
Pain 9 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Lower Urinary Tract Symptoms 54 91.60 High High
Overactive Bladder 99 89.04 High High
Benign Prostatic Hypertrophy 72 87.20 High High
Nervous System Injury 18 67.76 Quite High
Glaucoma 9 23.60 Low Low
Apoptosis 18 9.20 Low Low
INFLAMMATION 18 8.32 Low Low
Increased Venous Pressure Under Development 9 6.96 Low Low
Stress 45 5.00 Very Low Very Low Very Low
Stress Incontinence 36 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In this study, we detected the over-expression of three proteins (OPTN, thioredoxin and preprohaptoglobin), and the under-expression of four proteins (peroxiredoxin 2, transgelin [SM22 alpha], HCNP, and beta-galactoside-binding lectin).
Gene_expression (over) of OPTN
1) Confidence 0.47 Published 2005 Journal Journal of Korean Medical Science Section Body Doc Link PMC2779299 Disease Relevance 0.33 Pain Relevance 0.07
In this study, we detected the over-expression of three proteins (OPTN, thioredoxin and preprohaptoglobin), and the under-expression of four proteins (peroxiredoxin 2, transgelin [SM22 alpha], HCNP, and beta-galactoside-binding lectin).
Gene_expression (expression) of OPTN
2) Confidence 0.47 Published 2005 Journal Journal of Korean Medical Science Section Body Doc Link PMC2779299 Disease Relevance 0.33 Pain Relevance 0.07
A comparison of bladder of BOO group with control bladder showed that three proteins of optineurin, thioredoxin and preprohaptoglobin were over-expressed in the bladder of BOO group.
Gene_expression (expressed) of optineurin in bladder
3) Confidence 0.47 Published 2005 Journal Journal of Korean Medical Science Section Abstract Doc Link PMC2779299 Disease Relevance 0.29 Pain Relevance 0
In this study, we detected the over-expression of three proteins (OPTN, thioredoxin and preprohaptoglobin), and the under-expression of four proteins (peroxiredoxin 2, transgelin [SM22 alpha], HCNP, and beta-galactoside-binding lectin).
Gene_expression (-) of OPTN
4) Confidence 0.47 Published 2005 Journal Journal of Korean Medical Science Section Body Doc Link PMC2779299 Disease Relevance 0.33 Pain Relevance 0.07
A comparison of images of proteins from bladders of obstructed rats with those of the controls showed that three proteins, optineurin (OPTN), thioredoxin and preprohaptoglobin, were over-expressed in the bladders of obstructed rats.
Gene_expression (expressed) of optineurin in bladders
5) Confidence 0.41 Published 2005 Journal Journal of Korean Medical Science Section Body Doc Link PMC2779299 Disease Relevance 0.05 Pain Relevance 0
Of the changes in protein expression detected in this proteomic analysis, the over-expression of OPTN and the under-expression of transgelin and HCNP were most noteworthy (Fig. 5) (Table 1, 2).


Gene_expression (over) of OPTN
6) Confidence 0.41 Published 2005 Journal Journal of Korean Medical Science Section Body Doc Link PMC2779299 Disease Relevance 0.42 Pain Relevance 0
A comparison of images of proteins from bladders of obstructed rats with those of the controls showed that three proteins, optineurin (OPTN), thioredoxin and preprohaptoglobin, were over-expressed in the bladders of obstructed rats.
Gene_expression (expressed) of OPTN in bladders
7) Confidence 0.41 Published 2005 Journal Journal of Korean Medical Science Section Body Doc Link PMC2779299 Disease Relevance 0.05 Pain Relevance 0
Of the changes in protein expression detected in this proteomic analysis, the over-expression of OPTN and the under-expression of transgelin and HCNP were most noteworthy (Fig. 5) (Table 1, 2).


Gene_expression (expression) of OPTN
8) Confidence 0.41 Published 2005 Journal Journal of Korean Medical Science Section Body Doc Link PMC2779299 Disease Relevance 0.42 Pain Relevance 0
Of the changes in protein expression detected in this proteomic analysis, the over-expression of OPTN and the under-expression of transgelin and HCNP were most noteworthy (Fig. 5) (Table 1, 2).


Gene_expression (-) of OPTN
9) Confidence 0.41 Published 2005 Journal Journal of Korean Medical Science Section Body Doc Link PMC2779299 Disease Relevance 0.42 Pain Relevance 0

General Comments

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