INT287654

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Context Info
Confidence 0.00
First Reported 2009
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 7
Disease Relevance 1.99
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Opa1) mitochondrion organization (Opa1) GTPase activity (Opa1)
Opa1 (Mus musculus)
Arigg1 (Mus musculus)
Pain Link Frequency Relevance Heat
pain pelvic 7 5.00 Very Low Very Low Very Low
Inflammation 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sprains And Strains 273 99.48 Very High Very High Very High
Infection 126 81.64 Quite High
Gonorrhea 91 75.00 Quite High
Chlamydia Infection 35 59.92 Quite High
Neuroleptic Malignant Syndrome 63 5.00 Very Low Very Low Very Low
Bardet-biedl Syndrome 42 5.00 Very Low Very Low Very Low
Immunization 21 5.00 Very Low Very Low Very Low
Reprotox - General 3 14 5.00 Very Low Very Low Very Low
Stress Incontinence 7 5.00 Very Low Very Low Very Low
Adhesions 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Antibodies to the 4L peptide did not bind Opa-expressing bacteria.
Opa Neg (not) Binding (bind) of Antibodies
1) Confidence 0.00 Published 2009 Journal PLoS ONE Section Abstract Doc Link PMC2779592 Disease Relevance 0.31 Pain Relevance 0
These antibodies could potentially recognize many Opa variants produced by different gonococcal strains and therefore, the use of different adjuvants or other strategies to induce high titered SV loop-specific antibodies with bactericidal activity that can be delivered systemically is warranted.
Opa Binding (recognize) of antibodies associated with sprains and strains
2) Confidence 0.00 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2779592 Disease Relevance 0.53 Pain Relevance 0
We conclude that an SV loop-specific cyclic peptide can be used to induce antibodies that recognize a broad spectrum of antigenically distinct Opa variants and have agglutination abilities.
Opa Binding (recognize) of antibodies
3) Confidence 0.00 Published 2009 Journal PLoS ONE Section Abstract Doc Link PMC2779592 Disease Relevance 0.16 Pain Relevance 0
We conclude that an SV loop-specific cyclic peptide can be used to induce antibodies that recognize a broad spectrum of antigenically distinct Opa variants and have agglutination abilities.
Opa Binding (recognize) of antibodies
4) Confidence 0.00 Published 2009 Journal PLoS ONE Section Abstract Doc Link PMC2779592 Disease Relevance 0.16 Pain Relevance 0
Antibodies against linear or cyclic peptides that correspond to the SV loop recognized intact gonococci as assessed by two different methods, and promisingly, antibodies generated against cyclic SV peptides bound the surface of 6 of the 8 Opa variants of strain FA1090, including Opa variants with 7 amino acid differences from the target peptide.
Opa Binding (bound) of antibodies associated with sprains and strains
5) Confidence 0.00 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2779592 Disease Relevance 0.33 Pain Relevance 0
The semi-quantitative surface-binding immunoblot (SBI) assay, which utilizes whole gonococci, was used to compare the concentration of antibodies needed for detectable binding to the different Opa variants of strain FA1090.
Opa Binding (binding) of antibodies associated with sprains and strains
6) Confidence 0.00 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2779592 Disease Relevance 0.18 Pain Relevance 0
Antibodies against linear or cyclic peptides that correspond to the SV loop recognized intact gonococci as assessed by two different methods, and promisingly, antibodies generated against cyclic SV peptides bound the surface of 6 of the 8 Opa variants of strain FA1090, including Opa variants with 7 amino acid differences from the target peptide.
Opa Binding (bound) of antibodies associated with sprains and strains
7) Confidence 0.00 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2779592 Disease Relevance 0.33 Pain Relevance 0

General Comments

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