INT287686

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.36
First Reported 2009
Last Reported 2010
Negated 0
Speculated 2
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.08
Pain Relevance 0.86

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein complex (Syp)
Anatomy Link Frequency
synapses 4
Syp (Rattus norvegicus)
Pain Link Frequency Relevance Heat
amygdala 294 99.84 Very High Very High Very High
ischemia 50 90.84 High High
long-term potentiation 26 66.20 Quite High
Inflammation 8 66.00 Quite High
antagonist 12 50.48 Quite High
Glutamate 7 5.00 Very Low Very Low Very Low
Inflammatory response 6 5.00 Very Low Very Low Very Low
Hippocampus 6 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Brain Hemorrhage 3 90.84 High High
Anxiety Disorder 152 89.52 High High
Targeted Disruption 3 80.80 Quite High
Stroke 10 66.96 Quite High
INFLAMMATION 14 66.00 Quite High
Cv Unclassified Under Development 46 53.76 Quite High
Brain Injury 4 32.16 Quite Low
Cognitive Disorder 1 29.60 Quite Low
Shock 40 5.00 Very Low Very Low Very Low
Overdose 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Following infusion, rats were trained, then sacrificed 24 hours after training as in our previous experiments, and Western blotting was performed on LA homogenates to determine whether training-induced activation of GluR1, synapsin, and synaptophysin at LA synapses is regulated by intra-LA infusion of each of these drugs (Figure 5a).
Spec (whether) Positive_regulation (induced) of Spec (whether) Positive_regulation (activation) of synaptophysin in synapses associated with amygdala
1) Confidence 0.36 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2888610 Disease Relevance 0.17 Pain Relevance 0.36
Western blotting on tissue taken from around the cannula tips in the LA was then performed to determine whether training-induced activation of GluR1, synapsin, and synaptophysin at LA synapses is regulated by intra-LA infusion of each of these drugs.
Spec (whether) Positive_regulation (induced) of Spec (whether) Positive_regulation (activation) of synaptophysin in synapses associated with amygdala
2) Confidence 0.36 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2888610 Disease Relevance 0.55 Pain Relevance 0.39
Although not investigated directly here, BDNF production may be coupled to GAP-43 and synaptophysin inductions in several ways.
Positive_regulation (coupled) of Positive_regulation (inductions) of synaptophysin
3) Confidence 0.12 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2779656 Disease Relevance 0.36 Pain Relevance 0.11

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox