INT287751

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Context Info
Confidence 0.01
First Reported 2009
Last Reported 2009
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.48
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Lpar1) mRNA processing (Rbm39) RNA binding (Rbm39)
plasma membrane (Lpar1) nucleus (Rbm39) cytoplasm (Lpar1)
Anatomy Link Frequency
epithelial cells 2
Rbm39 (Mus musculus)
Lpar1 (Mus musculus)
Pain Link Frequency Relevance Heat
allodynia 5 95.64 Very High Very High Very High
Thermal hyperalgesia 2 94.64 High High
Spinal cord 39 90.32 High High
Central nervous system 1 47.28 Quite Low
Neuropathic pain 12 10.88 Low Low
Sciatic nerve 8 5.00 Very Low Very Low Very Low
Pain 7 5.00 Very Low Very Low Very Low
spinal dorsal horn 5 5.00 Very Low Very Low Very Low
intrathecal 5 5.00 Very Low Very Low Very Low
Demyelination 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ovarian Cancer 4 99.24 Very High Very High Very High
Neuropathic Pain 17 95.64 Very High Very High Very High
Hyperalgesia 5 94.64 High High
Nociception 3 92.56 High High
Nervous System Injury 2 50.00 Quite Low
Ganglion Cysts 9 5.00 Very Low Very Low Very Low
Pain 7 5.00 Very Low Very Low Very Low
Demyelinating Disease 5 5.00 Very Low Very Low Very Low
Urological Neuroanatomy 5 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This result is consistent with previous reports suggesting that LPA2 and LPA3 receptors might contribute to LPA-induced LPA production in ovarian cancer cells, because ovarian cancer cells express high levels of LPA2 and LPA3 receptors whereas normal ovarian epithelial cells express low levels of LPA2 and LPA3 receptors [41-43].
receptors Spec (might) Positive_regulation (contribute) of Positive_regulation (induced) of LPA-induced in epithelial cells associated with ovarian cancer
1) Confidence 0.01 Published 2009 Journal Mol Pain Section Body Doc Link PMC2780384 Disease Relevance 0.48 Pain Relevance 0.39

General Comments

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