INT287795

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Context Info
Confidence 0.05
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 2.71
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
plasma cells 1
FAM190B (Homo sapiens)
Pain Link Frequency Relevance Heat
fibrosis 41 99.24 Very High Very High Very High
Bile 18 96.28 Very High Very High Very High
Inflammation 21 78.12 Quite High
Chronic pancreatitis 10 5.00 Very Low Very Low Very Low
imagery 6 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
positron emission tomography 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatitis 169 99.66 Very High Very High Very High
Fibrosis 29 99.24 Very High Very High Very High
Disease 40 96.28 Very High Very High Very High
Loss Of Sense Of Smell 1 93.88 High High
Salivary Gland Disease 12 93.72 High High
Thyroid Disease 1 93.40 High High
Sensorineural Hearing Loss 1 92.64 High High
Purpura 1 90.80 High High
Sclerosing Cholangitis 17 88.92 High High
Sialadenitis 19 87.52 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
By histologically and immunohistochemically examining various organs of AIP patients, dense infiltration of IgG4-positive plasma cells as well as CD4- or CD8-positive T lymphocytes and fibrosis have been observed in the peripancreatic retroperitoneal tissue, bile duct wall, gallbladder wall, periportal area of the liver, salivary glands, as well as the pancreas of AIP patients.7,8,32 All extrapancreatic lesions associated with AIP such as sclerosing cholangitis, sclerosing sialadenitis, or retroperitoneal fibrosis show infiltration of abundant IgG4-positive plasma cells, but the infiltration is not detected in those of PSC, Sjögren’s syndrome, sialolithiasis, chronic alcoholic pancreatitis, or pancreatic cancer.
Localization (infiltration) of CD8-positive in plasma cells associated with bile, syndrome, salivary gland disease, primary sclerosing cholangitis, pancreatitis, sclerosing cholangitis, fibrosis, retroperitoneal fibrosis, pancreatic cancer, alcoholic pancreatitis, salivary gland calculi and sialadenitis
1) Confidence 0.05 Published 2006 Journal J Gastroenterol Section Body Doc Link PMC2780632 Disease Relevance 2.71 Pain Relevance 0.33

General Comments

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