INT287814

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Context Info
Confidence 0.03
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.15
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (Apex1, Rnf128) cytoplasm (Apex1, Rnf128) nucleoplasm (Apex1)
mitochondrion (Apex1) lyase activity (Apex1) aging (Apex1)
Anatomy Link Frequency
T-cell 2
Apex1 (Mus musculus)
Rnf128 (Mus musculus)
Pain Link Frequency Relevance Heat
Arthritis 27 69.84 Quite High
cytokine 24 38.52 Quite Low
antagonist 4 35.92 Quite Low
rheumatoid arthritis 34 5.00 Very Low Very Low Very Low
Inflammation 18 5.00 Very Low Very Low Very Low
imagery 7 5.00 Very Low Very Low Very Low
chemokine 5 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
methotrexate 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Lymphoproliferative Disease 1 79.48 Quite High
Arthritis 29 69.84 Quite High
INFLAMMATION 22 39.12 Quite Low
Disease 9 34.16 Quite Low
Rheumatoid Arthritis 34 5.00 Very Low Very Low Very Low
Autoimmune Disease 17 5.00 Very Low Very Low Very Low
Multiple Sclerosis 3 5.00 Very Low Very Low Very Low
Apoptosis 2 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low
Toxicity 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recently, Anandasabapathy et al. have identified a new gene named GRAIL (gene related to anergy in lymphocytes).45 They have demonstrated that retrovirally transduced T-cell hybridomas that expressed GRAIL showed a blockade in Il-2 transcription, and CD4+CD25+ Treg cells also express GRAIL after activation (Ref. 46, and unpublished data).
Ref Positive_regulation (activation) of Gene_expression (express) of GRAIL in T-cell
1) Confidence 0.03 Published 2006 Journal Mod Rheumatol Section Body Doc Link PMC2780633 Disease Relevance 0.15 Pain Relevance 0.03

General Comments

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