INT287875

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Context Info
Confidence 0.04
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.51
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (EP300, HDAC9) nucleus (EP300, HDAC9) transcription factor binding (EP300, HDAC9)
nucleoplasm (EP300) transferase activity, transferring acyl groups (EP300) DNA binding (EP300)
EP300 (Homo sapiens)
HDAC9 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 13 5.00 Very Low Very Low Very Low
aspirin 7 5.00 Very Low Very Low Very Low
antagonist 7 5.00 Very Low Very Low Very Low
Kinase C 6 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
vincristine 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 81 86.88 High High
Apoptosis 18 85.80 High High
Solid Tumor 1 83.28 Quite High
Repression 1 73.84 Quite High
Colon Cancer 10 62.64 Quite High
Adenoma 2 55.76 Quite High
Carcinoma 2 46.88 Quite Low
Malignant Neoplastic Disease 2 26.24 Quite Low
Leukemia 2 19.16 Low Low
Colorectal Cancer 18 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Through inhibiting HDAC, CBP/P300 will no longer be able to function as a co-activator, and possibly even repress the ?
P300 Negative_regulation (inhibiting) of HDAC
1) Confidence 0.04 Published 2006 Journal Invest New Drugs Section Body Doc Link PMC2780666 Disease Relevance 0.51 Pain Relevance 0

General Comments

This test has worked.

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