INT287882

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Context Info
Confidence 0.01
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.85
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (CREBBP, HNF4A) DNA binding (CREBBP, HNF4A) cytoplasm (CREBBP, HNF4A)
nucleus (CREBBP, HNF4A) cell differentiation (HNF4A) small molecule metabolic process (CREBBP)
CREBBP (Homo sapiens)
HNF4A (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 26 5.00 Very Low Very Low Very Low
aspirin 14 5.00 Very Low Very Low Very Low
antagonist 14 5.00 Very Low Very Low Very Low
Kinase C 12 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
agonist 4 5.00 Very Low Very Low Very Low
Arthritis 4 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
vincristine 2 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 36 99.32 Very High Very High Very High
Repression 2 87.36 High High
Cancer 162 62.72 Quite High
Carcinoma 4 60.40 Quite High
Solid Tumor 2 59.12 Quite High
Malignant Neoplastic Disease 4 39.76 Quite Low
Colon Cancer 20 38.48 Quite Low
Leukemia 4 32.68 Quite Low
Adenoma 4 31.60 Quite Low
Colorectal Cancer 36 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In Drosophila, Tcf has been shown to interact with CBP (CREB binding protein, histone acetylase), thereby repressing gene transcription when Wnt signaling is inactive [131].
CBP Binding (interact) of Tcf
1) Confidence 0.01 Published 2006 Journal Invest New Drugs Section Body Doc Link PMC2780666 Disease Relevance 0.42 Pain Relevance 0
In Drosophila, Tcf has been shown to interact with CBP (CREB binding protein, histone acetylase), thereby repressing gene transcription when Wnt signaling is inactive [131].
CREB binding protein Binding (interact) of Tcf
2) Confidence 0.01 Published 2006 Journal Invest New Drugs Section Body Doc Link PMC2780666 Disease Relevance 0.43 Pain Relevance 0

General Comments

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