INT287886

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Context Info
Confidence 0.00
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.19
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (THEMIS, PRKCA) nucleus (THEMIS, PRKCA) nucleoplasm (PRKCA)
mitochondrion (PRKCA) small molecule metabolic process (PRKCA) endoplasmic reticulum (PRKCA)
THEMIS (Homo sapiens)
PRKCA (Homo sapiens)
Pain Link Frequency Relevance Heat
Kinase C 6 100.00 Very High Very High Very High
vincristine 1 56.08 Quite High
cINOD 13 5.00 Very Low Very Low Very Low
aspirin 7 5.00 Very Low Very Low Very Low
antagonist 7 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Skin Cancer 5 99.92 Very High Very High Very High
Breast Cancer 4 95.36 Very High Very High Very High
Cancer 81 89.92 High High
Targeted Disruption 2 86.76 High High
Apoptosis 18 68.48 Quite High
Lung Cancer 4 32.72 Quite Low
Colorectal Cancer 18 5.00 Very Low Very Low Very Low
Disease 18 5.00 Very Low Very Low Very Low
Colon Cancer 10 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Blocking this pathway using antibodies to Fzd5, a receptor for Wnt5a, was shown to inhibit PKC activity and cellular invasion.
Negative_regulation (Blocking) of pathway Negative_regulation (inhibit) of PKC associated with kinase c
1) Confidence 0.00 Published 2006 Journal Invest New Drugs Section Body Doc Link PMC2780666 Disease Relevance 1.19 Pain Relevance 0.08

General Comments

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