INT287892

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Context Info
Confidence 0.00
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.52
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (PRDX2, HNF4A) cell differentiation (HNF4A) nucleoplasm (HNF4A)
mitochondrion (PRDX2) oxidoreductase activity (PRDX2) nucleus (HNF4A)
Anatomy Link Frequency
SW620 1
PRDX2 (Homo sapiens)
HNF4A (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 13 5.00 Very Low Very Low Very Low
aspirin 7 5.00 Very Low Very Low Very Low
antagonist 7 5.00 Very Low Very Low Very Low
Kinase C 6 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
vincristine 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 18 100.00 Very High Very High Very High
Carcinoma 2 100.00 Very High Very High Very High
Malignant Neoplastic Disease 2 82.80 Quite High
Cancer 81 81.52 Quite High
Leukemia 2 75.72 Quite High
Repression 1 49.04 Quite Low
Colon Cancer 10 47.16 Quite Low
Toxicity 1 34.04 Quite Low
Adhesions 3 16.48 Low Low
Metastasis 4 12.92 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It has been shown that sodium butyrate and Trichostatin A (TSA), inducers of G0–G1 cell cycle arrest and apoptosis in the SW620 colonic carcinoma cell line, up-regulate Tcf activity.
TSA Positive_regulation (up-regulate) of Tcf in SW620 associated with carcinoma and apoptosis
1) Confidence 0.00 Published 2006 Journal Invest New Drugs Section Body Doc Link PMC2780666 Disease Relevance 0.52 Pain Relevance 0

General Comments

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