INT287894

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Context Info
Confidence 0.04
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 2.49
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (VEGFA, BMP4) growth (VEGFA, BMP4) extracellular region (VEGFA, BMP4)
proteinaceous extracellular matrix (VEGFA, BMP4) cytoplasm (VEGFA)
VEGFA (Homo sapiens)
BMP4 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 4 99.60 Very High Very High Very High
cINOD 52 5.00 Very Low Very Low Very Low
aspirin 28 5.00 Very Low Very Low Very Low
antagonist 28 5.00 Very Low Very Low Very Low
Kinase C 24 5.00 Very Low Very Low Very Low
Inflammation 8 5.00 Very Low Very Low Very Low
agonist 8 5.00 Very Low Very Low Very Low
Arthritis 8 5.00 Very Low Very Low Very Low
withdrawal 4 5.00 Very Low Very Low Very Low
vincristine 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 324 90.88 High High
Apoptosis 72 88.64 High High
Hepatocellular Cancer 4 63.40 Quite High
Colorectal Cancer 72 60.80 Quite High
Chromosomal Instability 4 51.52 Quite High
Skin Cancer 20 8.48 Low Low
Medulloblastoma 4 6.48 Low Low
Liver Cancer 4 5.80 Low Low
Disease 72 5.00 Very Low Very Low Very Low
Colon Cancer 40 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Other target genes that have been identified include, for instance, vascular endothelial growth factor (VEGF), Wnt-1 induced secreted protein 1 (WISP-1), Bone morphogenetic protein-4 (BMP-4), matrix metalloproteinase (MMP) 7 and 26.
VEGF Positive_regulation (induced) of Localization (secreted) of Bone morphogenetic protein-4 associated with metalloproteinase
1) Confidence 0.04 Published 2006 Journal Invest New Drugs Section Body Doc Link PMC2780666 Disease Relevance 0.62 Pain Relevance 0.05
Other target genes that have been identified include, for instance, vascular endothelial growth factor (VEGF), Wnt-1 induced secreted protein 1 (WISP-1), Bone morphogenetic protein-4 (BMP-4), matrix metalloproteinase (MMP) 7 and 26.
vascular endothelial growth factor Positive_regulation (induced) of Localization (secreted) of Bone morphogenetic protein-4 associated with metalloproteinase
2) Confidence 0.04 Published 2006 Journal Invest New Drugs Section Body Doc Link PMC2780666 Disease Relevance 0.63 Pain Relevance 0.05
Other target genes that have been identified include, for instance, vascular endothelial growth factor (VEGF), Wnt-1 induced secreted protein 1 (WISP-1), Bone morphogenetic protein-4 (BMP-4), matrix metalloproteinase (MMP) 7 and 26.
vascular endothelial growth factor Positive_regulation (induced) of Localization (secreted) of BMP-4 associated with metalloproteinase
3) Confidence 0.04 Published 2006 Journal Invest New Drugs Section Body Doc Link PMC2780666 Disease Relevance 0.63 Pain Relevance 0.05
Other target genes that have been identified include, for instance, vascular endothelial growth factor (VEGF), Wnt-1 induced secreted protein 1 (WISP-1), Bone morphogenetic protein-4 (BMP-4), matrix metalloproteinase (MMP) 7 and 26.
VEGF Positive_regulation (induced) of Localization (secreted) of BMP-4 associated with metalloproteinase
4) Confidence 0.04 Published 2006 Journal Invest New Drugs Section Body Doc Link PMC2780666 Disease Relevance 0.62 Pain Relevance 0.05

General Comments

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