INT287915

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Context Info
Confidence 0.06
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.37
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (HNF4A) nucleoplasm (HNF4A) nucleus (HNF4A)
DNA binding (HNF4A) cytoplasm (HNF4A)
HNF4A (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 13 5.00 Very Low Very Low Very Low
aspirin 7 5.00 Very Low Very Low Very Low
antagonist 7 5.00 Very Low Very Low Very Low
Kinase C 6 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
vincristine 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Repression 1 99.14 Very High Very High Very High
Apoptosis 18 82.24 Quite High
Carcinoma 2 71.32 Quite High
Malignant Neoplastic Disease 2 50.68 Quite High
Cancer 81 49.40 Quite Low
Leukemia 2 43.60 Quite Low
Solid Tumor 1 34.40 Quite Low
Colon Cancer 10 15.04 Low Low
Adenoma 2 6.88 Low Low
Colorectal Cancer 18 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
HDAC inhibitors such as butyrate and TSA, block this repression resulting in a reduction of the threshold necessary to activate Tcf transcription.
Positive_regulation (necessary) of Positive_regulation (activate) of Tcf associated with repression
1) Confidence 0.06 Published 2006 Journal Invest New Drugs Section Body Doc Link PMC2780666 Disease Relevance 0.37 Pain Relevance 0

General Comments

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